The Ottawa Hospital Research Institute, Ottawa, ON, Canada.
Division of Hematology, The Ottawa Hospital, Ottawa, ON, Canada.
Leuk Lymphoma. 2020 Jan;61(1):156-164. doi: 10.1080/10428194.2019.1646908. Epub 2019 Aug 7.
Patients with hematological malignancies (HM) or undergoing hematopoietic cell transplantation (HCT) require reliable vascular access. Peripherally inserted central catheters (PICC) meet this need, however, studies suggest these patients have higher rates of PICC-associated complications. This retrospective cohort study evaluates the influence of PICC type on the rates and incidences of complications. Four hundred and eighty-five dual lumen PICCs were inserted into 469 complex patients with HM or undergoing HCT: 161 Groshong, 60 PowerPICC Solo, 165 BioFlo, and 99 Arrow. The rates and incidences of complications differed significantly across the PICC types. The overall rate of complication ranged from 7.40 to 26.4/1000 catheter days (CDs). The rate of deep vein thrombosis (0.31-1.48/1000 CDs) and occlusion differed across the PICC types, while the rate of central line-associated bloodstream infection (0.53-0.74/1000 CDs) did not. Following multivariate adjustment, PICC type was associated with complication rate. This highlights that PICC type should be considered in clinical decisions.
患有血液系统恶性肿瘤（HM）或正在接受造血细胞移植（HCT）的患者需要可靠的血管通路。外周插入的中心导管（PICC）满足了这一需求，然而，研究表明这些患者的 PICC 相关并发症发生率更高。本回顾性队列研究评估了 PICC 类型对并发症发生率和发生率的影响。将 485 根双腔 PICC 插入 469 例 HM 复杂患者或正在接受 HCT 的患者中：161 根 Groshong、60 根 PowerPICC Solo、165 根 BioFlo 和 99 根 Arrow。不同 PICC 类型的并发症发生率和发生率存在显著差异。总体并发症发生率为 7.40 至 26.4/1000 导管日（CD）。深静脉血栓形成（0.31-1.48/1000 CDs）和闭塞的发生率在不同的 PICC 类型之间存在差异，而中心静脉相关血流感染的发生率（0.53-0.74/1000 CDs）则没有。多变量调整后，PICC 类型与并发症发生率相关。这突出表明，在临床决策中应考虑 PICC 类型。
