Department of Pediatric Surgery, Tokyo Medical and Dental University Hospital, 1-5-45, Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan.
Pediatr Surg Int. 2023 Sep 6;39(1):264. doi: 10.1007/s00383-023-05545-4.
Tunneled central venous catheters (TCVs) are commonly used for pediatric chemotherapy. Recently, peripherally inserted central catheters (PICCs) have been used instead. Although PICC has the advantages of simpler insertion and fewer severe complications, there is little information on the efficacy of PICC compared to TCV in pediatric chemotherapy.
Patients, aged younger than 18 years, with primary malignancy who received chemotherapy with PICC or TCV at our institution from December 2007 to August 2022 were included in the study. We retrospectively compared PICC and TCV using medical records.
Within the observation period, 133 catheters (73 PICCs and 60 TCVs) were inserted. The median indwelling time was 99 days for PICCs and 182 days for TCVs, with TCVs being significantly longer (p < 0.001). There were no significant differences in the incidence of complications, such as infections, thrombosis, obstruction, or mechanical accidents. Comparing patients treated with PICC (PICC group) versus those with TCV (TCV group), the time from diagnosis to insertion was significantly shorter in the PICC group (p < 0.001). In the PICC group, none of the patients required general anesthesia, and chemotherapy was completed with PICC only.
PICC can be an alternative to TCV in pediatric chemotherapy.
经外周静脉穿刺中心静脉置管（PICC）常用于儿科化疗。近年来，已开始使用外周静脉置入中心导管（PICC）。虽然 PICC 具有插入操作更简单、严重并发症更少的优点，但与 TCV 相比，其在儿科化疗中的疗效的相关信息较少。
本研究纳入了 2007 年 12 月至 2022 年 8 月期间在我院接受 PICC 或 TCV 化疗的年龄小于 18 岁的初治恶性肿瘤患者。我们通过病历回顾比较了 PICC 和 TCV。
在观察期间，共置入 133 根导管（73 根 PICC 和 60 根 TCV）。PICC 的中位留置时间为 99 天，TCV 为 182 天，TCV 明显更长（p<0.001）。感染、血栓形成、阻塞或机械事故等并发症的发生率无显著差异。比较接受 PICC（PICC 组）和 TCV（TCV 组）治疗的患者，PICC 组从诊断到置管的时间明显更短（p<0.001）。在 PICC 组中，无一例患者需要全身麻醉，仅通过 PICC 完成化疗。
PICC 可作为儿科化疗中 TCV 的替代方法。
