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2018 年沙赫鲁德市男性驾驶员中代谢综合征与阻塞性睡眠呼吸暂停的关系评估:一项横断面研究。

Assessment of the relationship between metabolic syndrome and obstructive sleep apnea in male drivers of Shahroud city in 2018: a cross sectional study.

机构信息

School of Allied Medical Sciences, Semnan University of Medical Sciences, Semnan, Iran.

Occupational Sleep Research Center, Tehran University of Medical Sciences, Tehran, Iran.

出版信息

BMC Public Health. 2019 Aug 6;19(1):1058. doi: 10.1186/s12889-019-7361-5.

DOI:10.1186/s12889-019-7361-5
PMID:31387558
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6685249/
Abstract

BACKGROUND

Metabolic syndrome involves a set of metabolic risk factors that directly increases the risk of atherosclerotic cardiovascular disease. Physical inactivity due to driving can increase the risk of metabolic syndrome. It is also known that sleep disorders (sleep apnea) can result in MetS. Driving in Iran is considered a very popular but risky occupation, so paying attention to this profession is of special importance. Therefore, the researchers aimed to investigate the association between sleep disorders and metabolic syndrome in drivers in Shahroud city in 2018.

METHODS

This cross-sectional study was carried out on 948 drivers from Shahroud city in 2018. After obtaining consent from participants, 3 questionnaires including demographic, Epworth Sleepiness Scale and STOP-BANG were completed. Clinical and anthropometric measurements were assessed, including blood pressure, waist circumference, hip circumference, weight, height, and body mass index. In addition, blood was drawn to measure High Density Lipoprotein, Low Density Lipoprotein, Triglyceride, cholesterol, and Fasting Blood Sugar levels. The relationship between metabolic syndrome and sleep disorders was then studied. In this study, statistical analyses were performed using SPSS software version 23 at a significance level of 0.05.

RESULTS

Mean age of drivers was 44.15 ± 11.66 (years). The mean waist circumference and mean hip circumference in subjects with a Class 1 Driver's License (a certificate for trucks and buses) were higher than those with a Class 2 Driver's License (a certificate for motorcars, minibuses, vans, etc. (seating< 20)) (P = 0.01 and P = 0.003, respectively). Moreover, the BMI in subjects with a Class 1 Driver's License was higher compared to subjects with a Class 2 Driver's License. The correlation between metabolic syndrome with sleep apnea based on STOP-BANG questionnaire was significant (p < 0.001) irrespective of definition (ATP and IDF).

CONCLUSIONS

According to the results of this study, there was a bi-directional association between sleep disorders and Mets, so this group should pass periodic medical examinations and training courses. Moreover, their families should be informed of prevention and treatment of this syndrome.

摘要

背景

代谢综合征涉及一组代谢风险因素,这些因素直接增加了动脉粥样硬化性心血管疾病的风险。由于驾驶导致的身体活动不足会增加代谢综合征的风险。众所周知,睡眠障碍(睡眠呼吸暂停)也会导致 MetS。在伊朗,驾驶被认为是一种非常流行但有风险的职业,因此特别关注这一职业非常重要。因此,研究人员旨在 2018 年调查沙赫鲁德市驾驶员睡眠障碍与代谢综合征之间的关系。

方法

本横断面研究于 2018 年对沙赫鲁德市的 948 名驾驶员进行。在获得参与者同意后,填写了包括人口统计学、Epworth 嗜睡量表和 STOP-BANG 在内的 3 份问卷。评估了临床和人体测量学测量,包括血压、腰围、臀围、体重、身高和体重指数。此外,抽取血液以测量高密度脂蛋白、低密度脂蛋白、甘油三酯、胆固醇和空腹血糖水平。然后研究了代谢综合征与睡眠障碍之间的关系。在这项研究中,使用 SPSS 软件版本 23 在 0.05 的显著性水平下进行了统计分析。

结果

驾驶员的平均年龄为 44.15±11.66(岁)。具有 1 类驾驶执照(卡车和公共汽车证书)的受试者的平均腰围和平均臀围高于具有 2 类驾驶执照(汽车、小型公共汽车、货车等证书(座位<20 人)(P=0.01 和 P=0.003)。此外,1 类驾驶执照受试者的 BMI 高于 2 类驾驶执照受试者。根据 STOP-BANG 问卷,代谢综合征与睡眠呼吸暂停之间存在显著相关性(p<0.001),与定义(ATP 和 IDF)无关。

结论

根据这项研究的结果,睡眠障碍与 Mets 之间存在双向关联,因此该人群应定期进行体检和培训课程。此外,应告知其家属预防和治疗该综合征。

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