Gameiro Joana, Lopes José António
Division of Nephrology and Renal Transplantation, Department of Medicine, Centro Hospitalar Lisboa Norte, EPE, Av. Prof. Egas Moniz, 1649-035, Lisbon, Portugal.
Ann Intensive Care. 2019 Aug 6;9(1):87. doi: 10.1186/s13613-019-0561-4.
Acute kidney injury (AKI) is a complex syndrome defined by a decrease in renal function. The incidence of AKI has raised in the past decades, and it is associated with negative impact in patient outcomes in the short and long term. Considering the impact of AKI on patient prognosis, research has focused on methods to assess patients at risk for developing AKI, diagnose subclinical AKI, and on prevention and treatment strategies, for which it is crucial an understanding of pathophysiology the of AKI. In this review, we discuss the use of easily available parameters found in a complete blood count to detect patients at risk for developing AKI, to provide an early diagnosis of AKI, and to predict associated patient outcomes.
急性肾损伤（AKI）是一种由肾功能下降所定义的复杂综合征。在过去几十年中，AKI的发病率有所上升，并且它在短期和长期内均对患者的预后产生负面影响。考虑到AKI对患者预后的影响，研究集中在评估有发生AKI风险的患者、诊断亚临床AKI的方法以及预防和治疗策略上，而了解AKI的病理生理学对于这些方面至关重要。在本综述中，我们讨论了利用全血细胞计数中易于获得的参数来检测有发生AKI风险的患者、对AKI进行早期诊断以及预测相关患者预后的情况。
