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比较袖状胃切除术失败后的再次袖状胃切除术与 Roux-en-Y 胃旁路术。

Comparison of Repeat Sleeve Gastrectomy and Roux-en-Y Gastric Bypass in Case of Weight Loss Failure After Sleeve Gastrectomy.

机构信息

Department of Digestive, Esogastric and Bariatric Surgery, Bichat Claude Bernard University Hospital, 46 rue Henri Huchard, F-75018, Paris, France.

Department of Medical and Oral Sciences and Biotechnologies, "G.d'Annunzio" University, Via dei Vestini 31, 66100, Chieti, Italy.

出版信息

Obes Surg. 2019 Dec;29(12):3919-3927. doi: 10.1007/s11695-019-04123-9.

Abstract

BACKGROUND

Few series are available on the results of repeat sleeve gastrectomy (re-SG) and Roux-en-Y gastric bypass (RYGB) performed to manage the failure of primary sleeve gastrectomy (SG). The objective of this study was to compare the short- and medium-term outcomes of re-SG and RYGB after SG.

MATERIAL & METHODS: Between January 2010 and December 2017, patients undergoing re-SG (n = 61) and RYGB (n = 83) for failure of primary SG were included in this study. Revisional surgery was proposed for patients with insufficient excess weight loss (EWL ≤ 50%) or weight regain. The primary endpoint was the comparison of weight loss in the re-SG group and the RYGB group at the 1-year follow-up. The secondary endpoints were overall mortality and morbidity, specific morbidity, length of stay, weight loss, and correction of comorbidities.

RESULTS

The mean interval between SG and re-SG was 41.5 vs. 43.2 months between SG and RYGB (p = 0.32). The mean operative time was 103 min (re-SG group) vs. 129.4 min (RYGB group). One death (1.7%; re-SG group) and 25 complications (17.4%; 9 in the re-SG group, 16 in the RYGB group) were observed. At the 1 year, mean body mass index was 31.6 in the re-SG group and 32.5 in the RYGB group (p = 0.61) and excess weight loss was 69.5 vs. 61.2, respectively (p = 0.05).

CONCLUSION

Re-SG and RYGB as revisional surgery for SG are feasible with acceptable outcomes and similar results on weight loss on the first postoperative year.

摘要

背景

针对原发性袖状胃切除术(SG)失败后行重复袖状胃切除术(re-SG)和 Roux-en-Y 胃旁路术(RYGB)的结果,仅有少数系列报道。本研究旨在比较 SG 后行 re-SG 和 RYGB 的短期和中期结果。

材料和方法

2010 年 1 月至 2017 年 12 月,纳入因原发性 SG 失败而行 re-SG(n=61)和 RYGB(n=83)的患者。对 EWL≤50%或体重反弹的患者建议行修正手术。主要终点是 re-SG 组和 RYGB 组在 1 年随访时的体重减轻情况比较。次要终点是总体死亡率和发病率、特定发病率、住院时间、体重减轻和合并症的纠正。

结果

SG 与 re-SG 之间的平均间隔为 41.5 个月,SG 与 RYGB 之间的平均间隔为 43.2 个月(p=0.32)。手术时间平均为 103 分钟(re-SG 组)和 129.4 分钟(RYGB 组)。re-SG 组发生 1 例死亡(1.7%)和 25 例并发症(17.4%,9 例在 re-SG 组,16 例在 RYGB 组)。1 年后,re-SG 组和 RYGB 组的平均体重指数分别为 31.6 和 32.5(p=0.61),超重减轻量分别为 69.5%和 61.2%(p=0.05)。

结论

SG 后行 re-SG 和 RYGB 作为修正手术是可行的,具有可接受的结果,术后第 1 年体重减轻的效果相似。

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