Laboratoire de Chimie Organique et de Substances Naturelles, UFR Sciences des Structures de la Matière et Technologie, Université Félix Houphouët-Boigny, Abidjan, Cote d'Ivoire.
Equipe "Pharmacognosie-Chimie des Substances Naturelles" BioCIS, Univ. Paris-Sud, CNRS, Université Paris-Saclay, Châtenay-Malabry, France.
Nat Prod Res. 2021 Apr;35(8):1364-1371. doi: 10.1080/14786419.2019.1650354. Epub 2019 Aug 7.
During our research to contribute to the elucidation of the chemical composition of the root bark of , six non-nitrogenous cassane diterpenoids () were isolated and identified. Of these secondary metabolites, three have never been previously described: Cassan-13,15-dien-3-oxo-17-oic acid (), Cassan-15-en-[7,17]-γ-lactone () and 6-hydroxy-cassamic acid (). The other are known but, never isolated from the root barks of (Fabaceae): Cassan-13,15-dien-17-oic acid (), hydroxycassamic acid methyl esther () and cassamic acid (). Their structures were established according to the spectroscopic data (NMR 1D and 2D, HR-ESI-MS and IR), in comparison with those of literature. The originality of this study lies in the fact that three new natural molecules were isolated and identified. In addition, all the isolated compounds () were reported for the first time from the root barks of .
在我们的研究中，为了阐明的根皮的化学成分，我们分离并鉴定了六种非含氮的贝壳杉二萜（）。在这些次生代谢产物中，有三种以前从未被描述过：Cassan-13,15-dien-3-oxo-17-oic acid ()、Cassan-15-en-[7,17]-γ-lactone ()和 6-hydroxy-cassamic acid ()。其他三种虽然已知，但从未从（豆科）的根皮中分离出来：Cassan-13,15-dien-17-oic acid ()、hydroxycassamic acid methyl esther ()和 cassamic acid ()。根据光谱数据（NMR 1D 和 2D、HR-ESI-MS 和 IR）并与文献进行比较，确定了它们的结构。这项研究的新颖之处在于分离并鉴定了三种新的天然分子。此外，所有分离得到的化合物（）均首次从的根皮中报道。
