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卵巢类固醇细胞瘤——1例罕见病例报告及文献复习

Steroid Cell Tumor of the Ovary - A Rare Case Report and Review of Literature.

作者信息

Patil Vijayalaxmi S, VemiReddy Poojitha Ram, Taqdees Afra, Arakeri Surekha U

机构信息

Department of Pathology, BLDE (DU) Shri B. M. Patil Medical College, Hospital and Research Centre, Vijayapura, Karnataka, India.

出版信息

Int J Appl Basic Med Res. 2019 Jul-Sep;9(3):185-187. doi: 10.4103/ijabmr.IJABMR_299_18.

DOI:10.4103/ijabmr.IJABMR_299_18
PMID:31392185
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6652275/
Abstract

Steroid cell tumors of the ovary are extremely rare, accounting for only 0.1% of all ovarian tumors. Most steroid cell tumors secrete steroid hormones, and only about 10%-15% of patients are asymptomatic. The clinical presentation may take many forms, including abdominal pain, distention, irregular menstrual cycles, and hirsutism. Here, we present a case of a 60-year-old postmenopausal patient who presented with complaints of bleeding per vagina and abdominal pain for 4 months. Ultrasonography (USG) revealed a hypoechoic left adnexal mass measuring 65 mm × 40 mm × 30 mm. Based on these USG findings, the diagnosis of cystic lesion of the left ovary was made. Total abdominal hysterectomy with bilateral salpingo-oophorectomy was done, and the specimen was sent for histopathological analysis. On histopathology, diagnosis of steroid cell tumor-not otherwise specified was offered. This case is reported due to its rarity and its unusual presentation, together with a brief review of the literature of the same.

摘要

卵巢类固醇细胞瘤极为罕见,仅占所有卵巢肿瘤的0.1%。大多数类固醇细胞瘤分泌类固醇激素,只有约10%-15%的患者无症状。临床表现形式多样,包括腹痛、腹胀、月经周期不规律和多毛症。在此,我们报告一例60岁绝经后患者,主诉阴道出血和腹痛4个月。超声检查(USG)显示左附件区有一低回声肿块,大小为65 mm×40 mm×30 mm。根据这些USG检查结果,诊断为左卵巢囊性病变。行全腹子宫切除术及双侧输卵管卵巢切除术,并将标本送去做组织病理学分析。组织病理学检查诊断为未另行特指的类固醇细胞瘤。报道此病例是因其罕见性、不寻常的表现以及对相关文献的简要回顾。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3a0/6652275/c7b64317b795/IJABMR-9-185-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3a0/6652275/8b1d112fa608/IJABMR-9-185-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3a0/6652275/c7b64317b795/IJABMR-9-185-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3a0/6652275/8b1d112fa608/IJABMR-9-185-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b3a0/6652275/c7b64317b795/IJABMR-9-185-g002.jpg

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引用本文的文献

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3
A rare ovarian hilus cell tumour accompanying bilateral serous cystadenomas: report of a case.罕见的卵巢门细胞肿瘤伴双侧浆液性囊腺瘤:病例报告。

本文引用的文献

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一名患有严重雄激素过多症的绝经后女性,其一侧卵巢存在类固醇细胞瘤,对侧卵巢存在卵泡膜细胞瘤。
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Tumor-like lesions of the ovary associated with pregnancy.与妊娠相关的卵巢肿瘤样病变。
Int J Gynecol Pathol. 1993 Apr;12(2):108-15. doi: 10.1097/00004347-199304000-00004.
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Ovarian steroid cell tumors (not otherwise specified). A clinicopathological analysis of 63 cases.卵巢类固醇细胞瘤(未另作说明)。63例临床病理分析。
Am J Surg Pathol. 1987 Nov;11(11):835-45. doi: 10.1097/00000478-198711000-00002.
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Hilus cell tumor of the ovary. A clinicopathological analysis of 12 Reinke crystal-positive and nine crystal-negative cases.卵巢门细胞瘤。12例含雷氏晶体阳性及9例晶体阴性病例的临床病理分析。
Int J Gynecol Pathol. 1989;8(4):299-310.