Shiffman Saul, Scholl Sarah M
Smoking Research Group, Department of Psychology, University of Pittsburgh.
Exp Clin Psychopharmacol. 2020 Jun;28(3):271-275. doi: 10.1037/pha0000319. Epub 2019 Aug 8.
This study examines how well exposure in topography sessions correlates with exposure when smoking ad libitum in the field, by measuring material deposited on the filters of cigarettes smoked in the lab and in the field. The data were collected in a study of the effect of very low-nicotine-content versus normal-nicotine-content cigarettes in nondaily smokers. A total of 4,771 cigarette filters (323 from laboratory topography sessions, 4,448 from the field) from 123 nondaily smokers were analyzed. Optical scanning assessed density of deposits on cigarette filters, an indicator of smoke drawn through the cigarette and thus of exposure. Both during baseline, when participants smoked their own cigarettes, and during treatment, when smoking experimental cigarettes, lab and field exposure were well correlated (both rs = .62, p < .0001; r = .69, p < .0001, when analyzing all available data). Total puff volume also correlated with field exposure (p < .0001). In all analyses, exposure was slightly lower in the lab than in the field (p < .001). Exposure in laboratory topography sessions is a good indicator of exposure during ad libitum smoking in the field, both when smokers are smoking their own, varied, brands of cigarettes and when they are smoking uniform research cigarettes with very low or normal nicotine content. At least among nondaily smokers, topography measures of smokers' exposure are generalizable. (PsycInfo Database Record (c) 2020 APA, all rights reserved).
本研究通过测量在实验室和实地自由吸烟时沉积在香烟滤嘴上的物质,考察了地形学实验中的暴露与实地自由吸烟时的暴露之间的关联程度。数据收集于一项针对非每日吸烟者中低尼古丁含量香烟与正常尼古丁含量香烟效果的研究。对123名非每日吸烟者的总共4771个香烟滤嘴(323个来自实验室地形学实验,4448个来自实地)进行了分析。光学扫描评估了香烟滤嘴上沉积物的密度,这是通过香烟吸入烟雾的一个指标,因此也是暴露的指标。在基线期参与者吸自己的香烟时以及治疗期吸实验香烟时,实验室和实地的暴露都具有良好的相关性(在分析所有可用数据时,两者的rs = 0.62,p < 0.0001;r = 0.69,p < 0.0001)。总吸量也与实地暴露相关(p < 0.0001)。在所有分析中,实验室的暴露略低于实地(p < 0.001)。无论是吸烟者吸自己的各种品牌香烟,还是吸尼古丁含量极低或正常的统一研究用香烟时,实验室地形学实验中的暴露都是实地自由吸烟时暴露的良好指标。至少在非每日吸烟者中,吸烟者暴露的地形学测量结果具有普遍性。(PsycInfo数据库记录(c)2020美国心理学会,保留所有权利)