Department of Bariatric and Metabolic Surgery, Mohak Bariatrics and Robotics Center, Indore, India.
Department of Surgery and Anatomy, Center for Gastrointestinal Endoscopy, Ribeirão Preto Medical School, Ribeirão Preto, Brazil.
Dig Endosc. 2020 May;32(4):541-546. doi: 10.1111/den.13508. Epub 2019 Nov 1.
Endoscopic sleeve gastroplasty (ESG) is gaining acceptance as a non-surgical option for the treatment of obesity. However, its role is still not consolidated for all populations and the ideal indications are yet to be determined. We aimed to study the efficacy and safety of ESG in Indian patients.
We conducted a single-center retrospective study of obese patients who underwent consecutive ESG at our tertiary care center. Data on weight loss and adverse events at 1, 3, 6, and 12 months were collected and analyzed.
Fifty-three patients underwent ESG from March 2017 to October 2018. Eighty one percent of patients were female (43/53). Mean baseline age and body mass index were 40.54 ± 13.79 years and 34.78 ± 5.20 kg/m , respectively. Mean duration of procedure was 68.96 ± 11.19 min. Immediate postoperative complications included mainly epigastric pain (45.2%) and nausea (22.6%) but there was no serious adverse event. Average percentage of total weight loss (%TWL) was 8.26%, 11.96%, 14.25%, and 19.94% at 1, 3, 6, and 12 months, respectively. Eighty-eight percent of patients achieved >15% TWL at 12 months. Younger patients (<30 years old) and female patients had greater %TWL at 12 months (P = 0.01 and P = 0.021, respectively). Last 18 procedures were significantly faster than the first 35 cases (P = 0.01).
Endoscopic sleeve gastroplasty is effective and safe at promoting weight loss in the Indian population. Young age and female gender are related to better outcomes.
内镜下袖状胃切除术（ESG）作为一种非手术治疗肥胖的方法，正逐渐被人们接受。然而，其作用在所有人群中尚未得到巩固，理想的适应证仍有待确定。我们旨在研究 ESG 在印度患者中的疗效和安全性。
我们对在我们的三级保健中心连续进行 ESG 的肥胖患者进行了一项单中心回顾性研究。收集并分析了 1、3、6 和 12 个月时体重减轻和不良事件的数据。
2017 年 3 月至 2018 年 10 月期间，53 例患者接受了 ESG 治疗。81%的患者为女性（43/53）。患者的平均基线年龄和体重指数分别为 40.54±13.79 岁和 34.78±5.20kg/m²。手术平均持续时间为 68.96±11.19 分钟。术后即刻的主要并发症包括上腹痛（45.2%）和恶心（22.6%），但无严重不良事件。1、3、6 和 12 个月时的平均总体重减轻百分比（%TWL）分别为 8.26%、11.96%、14.25%和 19.94%。88%的患者在 12 个月时体重减轻超过 15%。年轻患者（<30 岁）和女性患者在 12 个月时的%TWL 更高（P=0.01 和 P=0.021）。最后 18 例手术明显快于前 35 例（P=0.01）。
ESG 在促进印度人群体重减轻方面是有效且安全的。年轻和女性与更好的结果相关。
