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不稳定的成熟膝关节骨软骨炎的内固定治疗有效吗?系统评价。

Does Internal Fixation for Unstable Osteochondritis Dissecans of the Skeletally Mature Knee Work? A Systematic Review.

机构信息

Department of Orthopedic Surgery, Mayo Clinic, Rochester, MN, U.S.A.

Department of Orthopaedics, Osaka University Graduate School of Medicine, Osaka, Japan.

出版信息

Arthroscopy. 2019 Aug;35(8):2512-2522. doi: 10.1016/j.arthro.2019.03.020.

Abstract

PURPOSE

To report the rate of radiographic union, patient-reported outcomes, complications, and reoperations after internal fixation of unstable osteochondritis dissecans (OCD) in the skeletally mature knee.

METHODS

A literature search was conducted according to Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines. Patients were included if they were skeletally mature and underwent internal fixation of an unstable OCD lesion of the knee. Risk of bias assessment was performed using the Methodological Index for Non-randomized Studies scoring system. Surgical technique, rate of union, patient-reported outcomes, complications, and reoperations were collected.

RESULTS

Thirteen studies resulted in 148 patients (150 knees) for inclusion. Patient age ranged from 14 to 45 years. Numerous fixation procedures were used, including biodegradable devices (rods, pins, nails, and screws), metal screws, Kirschner wire, and autologous bone sticks. Overall, reported outcome measures were heterogeneous in nature. The rate of radiographic healing ranged from 67% to 100% across 6 studies. Improved subjective results and Hughston criteria on final follow-up ranged from 83% to 100% across 4 studies each. Mean postoperative Lysholm scores ranged from 42 to 98 in studies that reported them. Both complication and reoperation rates ranged from 0% to 44%. The most commonly performed reoperations were loose body excision and cartilage resurfacing procedures.

CONCLUSIONS

A variety of surgical techniques are available for treatment of unstable OCD lesions in the skeletally mature knee. In this systematic review, internal fixation of the native fragment showed acceptable rates of radiographic union and improved patient-reported outcomes relative to other techniques.

LEVEL OF EVIDENCE

Level IV, systematic review of level III-IV studies.

摘要

目的

报告在骨骼成熟的膝关节中,对不稳定的剥脱性骨软骨炎(OCD)进行内固定后,影像学愈合率、患者报告的结局、并发症和再手术率。

方法

根据系统评价和荟萃分析的首选报告项目进行文献检索。纳入标准为骨骼成熟且行膝关节不稳定 OCD 病变内固定的患者。使用非随机研究方法学指数(Methodological Index for Non-randomized Studies scoring system)进行偏倚风险评估。收集手术技术、愈合率、患者报告的结局、并发症和再手术情况。

结果

13 项研究共纳入 148 例患者(150 膝)。患者年龄为 14 至 45 岁。使用了多种固定术式,包括生物可降解器械(棒、钉、钉和螺钉)、金属螺钉、克氏针和自体骨棒。总体而言,报告的结局指标性质各异。6 项研究中,影像学愈合率为 67%至 100%。4 项研究中,最终随访时主观结果和 Hughston 标准改善率为 83%至 100%。报告术后 Lysholm 评分的研究中,平均评分为 42 至 98。并发症和再手术率分别为 0%至 44%。最常进行的再手术是游离体切除和软骨表面重建术。

结论

骨骼成熟的膝关节中不稳定 OCD 病变的治疗方法多种多样。在本系统评价中,与其他技术相比,内固定原生骨碎片显示出可接受的影像学愈合率和改善的患者报告结局。

证据等级

IV 级,对 III-IV 级研究的系统评价。

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