Division of Nutritional Sciences, Cornell University, Ithaca, New York.
Department of Obstetrics and Gynecology, University of Rochester Medical Center, Rochester, New York.
Fertil Steril. 2019 Nov;112(5):939-946. doi: 10.1016/j.fertnstert.2019.06.016. Epub 2019 Aug 5.
To assess right-left differences in ultrasonographic markers of ovarian morphology and determine the impact on the diagnosis of polycystic ovarian morphology (PCOM).
A cross-sectional study of data collected from 2006 to 2018.
Academic clinical research centers.
PATIENT(S): Women with polycystic ovary syndrome (PCOS; n = 87) and controls (n = 67).
INTERVENTION(S): None.
MAIN OUTCOMES MEASURE(S): Follicle number per ovary (FNPO), follicle number per cross-section (FNPS), and ovarian volume (OV) were assessed in both ovaries using transvaginal ultrasonography. PCOM was identified based on recent international consensus guidelines or proposed diagnostic thresholds.
RESULT(S): Overall, mean right-left differences were two follicles for FNPO, one follicle for FNPS, and 2 mL for OV. FNPO showed the strongest correlation between ovaries. Its assessment in a single ovary did not impact the diagnosis of PCOM in women with PCOS. However, there were differences in the probability of unilateral versus bilateral PCOM based on FNPS and OV in both groups.
CONCLUSION(S): FNPO is the most reliable unilateral marker of PCOM in light of right-left differences in ovarian morphology. Use of FNPS or OV to define PCOM is discouraged when only one ovary is visualized.
评估卵巢形态超声标志物的左右差异，并确定其对多囊卵巢形态（PCOM）诊断的影响。
2006 年至 2018 年期间收集数据的横断面研究。
学术临床研究中心。
多囊卵巢综合征（PCOS；n=87）患者和对照组（n=67）。
无。
使用经阴道超声评估每侧卵巢的卵泡数（FNPO）、每横切面卵泡数（FNPS）和卵巢体积（OV）。根据最近的国际共识指南或提出的诊断阈值确定 PCOM。
总体而言，FNPO 的左右差异平均为 2 个卵泡，FNPS 为 1 个卵泡，OV 为 2 mL。FNPO 两个卵巢之间相关性最强。在 PCOS 患者中，单侧卵巢评估不影响 PCOM 的诊断。然而，根据 FNPS 和 OV，两组单侧与双侧 PCOM 的概率存在差异。
鉴于卵巢形态的左右差异，FNPO 是 PCOM 最可靠的单侧标志物。当仅可见一侧卵巢时，不建议使用 FNPS 或 OV 来定义 PCOM。
