Coutant Thomas, Laniesse Delphine, Sykes John M
Service NAC, CHV Fregis, 43 Avenue Aristide Briand, Arcueil 94110, France.
Eläinsairaala Evidensia Tammisto Vantaa, Tammiston Kauppatie 29, Vantaa 01510, Finland.
Vet Clin North Am Exot Anim Pract. 2019 Sep;22(3):501-520. doi: 10.1016/j.cvex.2019.05.006.
Reducing the frequency of drug administration in the treatment of exotic pets is advantageous because it may decrease handling frequency and thus potential stress and injury risk for the animal, increase owner compliance with the prescribed treatment, and decrease need for general anesthesia in patients that cannot be handled safely. Increasing efficient drug plasma concentration using sustained-released delivery systems is an appealing solution. Potential candidates that could provide a promising solution have been investigated in exotic pets. In this article, the technologies that are the closest to being integrated in exotic pet medicine are reviewed: osmotic pumps, nanoparticles, and hydrogels.
减少外来宠物治疗中药物给药频率具有优势，因为这可能会降低处理频率，从而降低动物潜在的应激和受伤风险，提高主人对规定治疗的依从性，并减少对无法安全处理的患者进行全身麻醉的需求。使用缓释给药系统提高药物有效血浆浓度是一个有吸引力的解决方案。在 exotic pets 中已经研究了可能提供有前景解决方案的潜在候选物。在本文中，对最接近整合到 exotic pet 医学中的技术进行了综述：渗透泵、纳米颗粒和水凝胶。
