Benadrostin, new inhibitor of poly(ADP-ribose) synthetase, produced by actinomycetes. II. Structure determination.
作者信息
Yoshida S, Naganawa H, Aoyagi T, Takeuchi T, Umezawa H
机构信息
Institute of Microbial Chemistry, Tokyo, Japan.
出版信息
J Antibiot (Tokyo). 1988 Aug;41(8):1015-8. doi: 10.7164/antibiotics.41.1015.
PMID:3139602
Abstract
Benadrostin, a new inhibitor of poly(ADP-ribose) synthetase, has been isolated from the culture broth of Streptomyces flavovirens MH499-O'F1. The structure of benadrostin was defined as 8-hydroxy-2H-1,3-benzoxazine-2,4-dione by an analysis of spectral properties and chemical studies of benadrostin and its derivatives.
摘要
Zotero 插件