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Role of formyl peptide receptor 2 (FPR2) in the normal brain and in neurological conditions.

作者信息

Ong Wei-Yi, Chua John Jia En

机构信息

Department of Anatomy, Yong Loo Lin School of Medicine, National University of Singapore; Life Sciences Institute Neurobiology Research Programme, National University of Singapore, Singapore.

Life Sciences Institute Neurobiology Research Programme; Department of Physiology, National University of Singapore; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Singapore.

出版信息

Neural Regen Res. 2019 Dec;14(12):2071-2072. doi: 10.4103/1673-5374.262575.

DOI:10.4103/1673-5374.262575
PMID:31397336
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6788234/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c0ee/6788234/d7959b0bece1/NRR-14-2071-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c0ee/6788234/d7959b0bece1/NRR-14-2071-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c0ee/6788234/d7959b0bece1/NRR-14-2071-g001.jpg

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Front Cell Neurosci. 2018 Nov 27;12:457. doi: 10.3389/fncel.2018.00457. eCollection 2018.
2
Lipoxin and Resolvin Receptors Transducing the Resolution of Inflammation in Cardiovascular Disease.脂氧素和消退素受体在心血管疾病中传导炎症消退作用
Front Pharmacol. 2018 Nov 14;9:1273. doi: 10.3389/fphar.2018.01273. eCollection 2018.
3
Early minor stimulation of microglial TLR2 and TLR4 receptors attenuates Alzheimer's disease-related cognitive deficit in rats: behavioral, molecular, and electrophysiological evidence.
CCL2 抑制促分解介质增强星形胶质细胞的神经炎症。
Int J Mol Sci. 2022 Mar 18;23(6):3307. doi: 10.3390/ijms23063307.
4
Triggering Innate Immune Receptors as New Therapies in Alzheimer's Disease and Multiple Sclerosis.触发先天免疫受体作为阿尔茨海默病和多发性硬化症的新疗法。
Cells. 2021 Aug 22;10(8):2164. doi: 10.3390/cells10082164.
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Annexin A1 protects against cerebral ischemia-reperfusion injury by modulating microglia/macrophage polarization via FPR2/ALX-dependent AMPK-mTOR pathway. annexin A1 通过 FPR2/ALX 依赖的 AMPK-mTOR 通路调节小胶质细胞/巨噬细胞极化,从而防止脑缺血再灌注损伤。
J Neuroinflammation. 2021 May 22;18(1):119. doi: 10.1186/s12974-021-02174-3.
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J Neuroinflammation. 2020 Aug 14;17(1):239. doi: 10.1186/s12974-020-01918-x.
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