作为死亡率预后因素的福尼尔坏疽病因：121例分析。

Etiology of Fournier gangrene as a prognostic factor in mortality: Analysis of 121 cases.

作者信息

Fernandez-Alcaraz D A, Guillén-Lozoya A H, Uribe-Montoya J, Romero-Mata R, Gutierrez-González A

机构信息

Departamento de Urología, Hospital Universitario Dr. Jose Eleuterio Gonzalez, Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, México.

Departamento de Urología, Hospital Regional Monterrey, Instituto de Seguridad y Servicios Sociales de los Trabjadores del Estado, Monterrey, Nuevo León, México.

出版信息

Actas Urol Esp (Engl Ed). 2019 Dec;43(10):557-561. doi: 10.1016/j.acuro.2019.05.006. Epub 2019 Aug 6.

DOI:10.1016/j.acuro.2019.05.006

PMID:31399259

Abstract

OBJECTIVE

Evaluate the origin of Fournier gangrene (FG) as a prognostic factor of morbidity and mortality.

MATERIAL AND METHODS

Patients who came to our clinic with a diagnosis of FG from 2010 to 2017 were included retrospectively. Patients were categorized depending on the origin of the infection. Three severity factors were determined in each group: days of hospital stay, the FG severity index, and mortality. Logistic regression test was performed to analyze the data.

RESULTS

Of the 130 patients evaluated, the origin was established in 121 based on the clinical history and radiological and surgical findings. Thirty-five patients had an intestinal origin with a mortality of 20.68%, 46 patients had a testicular origin with a mortality of 2.22%, 12 patients had a urinary origin with a mortality of 0%, and 28 patients with a cutaneous origin with a mortality of 16.6%. The testicular origin was the most frequent (38%) in addition to presenting a lower hospital stay, a lower FG severity index, and a lower mortality than those with an intestinal origin (P=.022).

CONCLUSIONS

The origin of the infection has a significant prognostic value in the mortality of the patient.

摘要

目的

评估福尼尔坏疽（FG）的感染源作为发病率和死亡率的预后因素。

材料与方法

回顾性纳入2010年至2017年到我院就诊且诊断为FG的患者。根据感染源对患者进行分类。在每组中确定三个严重程度因素：住院天数、FG严重程度指数和死亡率。进行逻辑回归测试以分析数据。

结果

在评估的130例患者中，根据临床病史以及放射学和手术结果，确定了121例患者的感染源。35例患者感染源为肠道，死亡率为20.68%；46例患者感染源为睾丸，死亡率为2.22%；12例患者感染源为泌尿，死亡率为0%；28例患者感染源为皮肤，死亡率为16.6%。除住院时间较短、FG严重程度指数较低以及死亡率低于肠道感染源患者外，睾丸感染源最为常见（38%）（P = 0.022）。