Institute of Human Genetics, Polish Academy of Sciences, Strzeszynska 32, 60-479, Poznan, Poland.
J Appl Genet. 2019 Nov;60(3-4):319-328. doi: 10.1007/s13353-019-00510-1. Epub 2019 Aug 10.
This review presents the state-of-the-art in the forensic application of genetic methods driven by the research in population transcriptomics. In the first part of the review, the constraints of using classical genomic markers are shortly reviewed. In the second part, the developments in the field of inter-population diversity at the transcriptomic level are presented. Subsequently, a potential of population-specific transcriptomic markers in forensic science applications, including ascertaining population affiliation of human samples and cell mixtures separation, are presented.
这篇综述介绍了基于群体转录组学研究的遗传方法在法医学应用中的最新进展。在综述的第一部分，简要回顾了使用经典基因组标记的限制。在第二部分，介绍了转录组水平上的种间多样性的发展。随后，提出了群体特异性转录组标记在法医学应用中的潜力，包括确定人类样本和细胞混合物的种群归属。
