Meyerhoff W L
Department of Otorhinolaryngology, University of Texas Health Center, Dallas 75235.
Otolaryngol Head Neck Surg. 1988 Jul;99(1):24-7. doi: 10.1177/019459988809900104.
In normal individuals, the visual and vestibular systems interact through a common subcortical center located near the vestibular nuclei. When the patient is healthy, this interaction allows appropriate integration of what might otherwise be conflicting information regarding environmental motion and moving within the environment. In patients with active peripheral vestibular lesions, such as those seen in Meniere's disease, this delicate interaction loses effectiveness. In such patients, optokinetic stimuli are capable of precipitating episodes of incapacitating vertigo with its associated vegetative symptoms (abnormal oculovestibular response--AOVR). Since the brainstem is unable to accommodate for active peripheral lesions, suffering may be prolonged for many years. Vestibular nerve section, however, converts this active lesion to a static peripheral lesion, allowing for brainstem compensation and cessation of optokinetic-induced vertiginous symptoms.
在正常个体中，视觉和前庭系统通过位于前庭核附近的一个共同的皮质下中枢相互作用。当患者健康时，这种相互作用能够对关于环境运动和在环境中移动的可能相互冲突的信息进行适当整合。在患有活动性外周前庭病变的患者中，如梅尼埃病患者所见，这种微妙的相互作用失去效力。在这类患者中，视动刺激能够引发使人丧失能力的眩晕发作及其相关的自主神经症状（异常眼前庭反应——AOVR）。由于脑干无法适应活动性外周病变，痛苦可能会持续多年。然而，前庭神经切断术将这种活动性病变转变为静态外周病变，使脑干得以代偿并消除视动诱发的眩晕症状。
