番石榴（L.）衰老叶片精油的化学成分和抗菌活性。

Chemical composition and antimicrobial activity of the essential oil of senescent leaves of guava ( L.).

机构信息

Department of Genetics and Plant Breeding, CSIR-Central Institute of Medicinal and Aromatic Plants, P.O. CIMAP, Lucknow, India.

Department of Process Chemistry and Technology, CSIR-Central Institute of Medicinal and Aromatic Plants, P.O. CIMAP, Lucknow, India.

出版信息

Nat Prod Res. 2021 Apr;35(8):1393-1397. doi: 10.1080/14786419.2019.1648462. Epub 2019 Aug 12.

DOI:10.1080/14786419.2019.1648462

PMID:31401871

Abstract

The aim of the study was to investigate the chemical composition and antimicrobial activity of the essential oil of the senescent leaves of L. (Myrtaceae). The hydrodistilled essential oil of the leaves was analysed by GC-FID and GC-MS. The antimicrobial activity of the oil was assessed against human and plant pathogenic microorganisms by disc diffusion, microdilution broth and poison food techniques. A total of forty-six constituents, representing 90.9% of the total oil composition were identified. Major constituents of the oil were limonene (29.1%), ()-caryophyllene (15.7%), caryophyllene oxide (8.8%), caryophylla-4(12),8(13)-dien-5-ol (6.5%), ()-nerolidol (4.0%), -cadinol (3.4%), and muurola-4,10(14)-dien-1--ol (2.5%). The chemical composition of the examined essential oil was quite different from those reported earlier. The essential oil showed significant inhibition of human pathogenic bacteria (MIC: 0.065-0.261 mg/mL) and plant pathogenic fungi, namely (86.02%) and (82.80%).

摘要

本研究旨在探讨衰老的柠檬桉（桃金娘科）叶片精油的化学成分和抗菌活性。采用 GC-FID 和 GC-MS 对叶片水蒸馏精油进行分析。采用圆盘扩散、微量稀释肉汤和毒饵技术评估油对人类和植物病原微生物的抗菌活性。共鉴定出 46 种成分，占总油组成的 90.9%。油的主要成分是柠檬烯（29.1%）、（）-石竹烯（15.7%）、石竹烯氧化物（8.8%）、石竹素-4(12),8(13)-二烯-5-醇（6.5%）、（）-香叶醇（4.0%）、-波旁二醇（3.4%）和穆罗莱-4,10(14)-二烯-1--醇（2.5%）。所检查的精油的化学成分与以前报道的相当不同。该精油对人类病原菌（MIC：0.065-0.261 mg/mL）和植物病原菌（86.02%）和（82.80%）具有显著的抑制作用。