Emara M K, Saadah A M
Department of Medicine, Mubarak Al Kabeer Hospital, Kuwait.
Postgrad Med J. 1988 Mar;64(749):191-2. doi: 10.1136/pgmj.64.749.191.
We report the development of the carpal tunnel syndrome in 3 hypertensive men (aged 46-58) treated with beta-blockers (propranolol in two patients and metoprolol in the 3rd) for 8-11 years. Known causes of carpal tunnel syndrome were excluded in each case. Withdrawal of the beta-blocker was followed by complete resolution of symptoms and signs after a period of 8-10 weeks. No evidence of recurrence could be detected during follow-up of 7-18 months. The possible mechanisms of drug-induced carpal tunnel syndrome are briefly discussed.
我们报告了3名高血压男性(年龄46 - 58岁)在使用β受体阻滞剂(2例使用普萘洛尔,第3例使用美托洛尔)治疗8 - 11年后出现腕管综合征的情况。在每例中均排除了已知的腕管综合征病因。停用β受体阻滞剂后,经过8 - 10周症状和体征完全消失。在7 - 18个月的随访中未发现复发迹象。本文简要讨论了药物性腕管综合征的可能机制。