Clarke Adolphus, Blidi Nicholas, Yokie Joseph, Momolu Mary, Agbo Chukwuemeka, Tuopileyi Roland, Rude Julius Monday, Seid Mohammed, Dereje Yohannes, Wambai Zakari, Gasasira Alex, Skrip Laura, Kennedy Ngozi, Lablah Evans, Okeibunor Joseph Chukwudi, Djingarey Mamoudou Harouna, Talisuna Ambrose, Yahaya Ali Ahmed, Rajatonirina Soatiana, Fall Ibrahima Socé
Ministry of Health, Monrovia, Liberia.
World Health Organization Country Office, Monrovia, Liberia.
Pan Afr Med J. 2019 May 28;33(Suppl 2):5. doi: 10.11604/pamj.supp.2019.33.2.17116. eCollection 2019.
The Ebola virus disease (EVD) outbreak in Liberia from 2014-2015 setback the already fragile health system which was recovering from the effects of civil unrest. This led to significant decline in immunization coverage and key polio free certification indicators. The Liberia investment plan was developed to restore immunization service delivery and overall health system.
We conducted a desk review to summarize performance of immunization coverage, polio eradication, measles control, new vaccines and technologies. Data sources include program reports, scientific and grey literature, District Health Information System (DHIS2), Integrated Diseases Surveillance and Response (IDSR) database, auto visual AFP detection and reporting (AVADAR) and ONA Servers. Data analysis was done using Microsoft excel spreadsheets, ONA software and Arc GIS.
There was a 36% increase in national coverage for Penta 3 in 2017 compared to 2014 from WUENIC data. Penta 3 dropout rate reduced by 2.5 fold from 15.3% in 2016 to 6.4% in 2017; while MCV1 coverage improved by 23% from 64% in 2015 to 87% in 2017. There was a rebound of non-polio AFP rate (NPAFP) rate from 1.2 in 2015 to 4.3 in 2017. Furthermore, there was a 2-fold increase in the number of AFP cases receiving 3 or more doses of OPV from 36% in 2015 to 61% in 2017.
Liberia demonstrated strong rebound of immunization services following the largest and most devastating EVD outbreak in West Africa in 2014 - 2015. Immunization coverage improved and dropout rates reduced. However, there are still opportunities for improvement in the immunization program both at national and sub-national levels.
2014 - 2015年利比里亚爆发的埃博拉病毒病（EVD）使本就脆弱且正从内乱影响中恢复的卫生系统遭受挫折。这导致免疫接种覆盖率和关键的无脊髓灰质炎认证指标大幅下降。利比里亚投资计划旨在恢复免疫服务提供及整体卫生系统。
我们进行了案头审查，以总结免疫接种覆盖率、脊髓灰质炎根除、麻疹控制、新疫苗及技术方面的表现。数据来源包括项目报告、科学文献和灰色文献、地区卫生信息系统（DHIS2）、综合疾病监测与应对（IDSR）数据库、自动可视急性弛缓性麻痹（AFP）检测与报告（AVADAR）以及ONA服务器。数据分析使用微软电子表格、ONA软件和Arc GIS进行。
根据西太区免疫监测与评价网络（WUENIC）数据，2017年五联疫苗第三剂次全国覆盖率相比2014年增长了36%。五联疫苗第三剂次的漏种率从2016年的15.3%降至2017年的6.4%，下降了2.5倍；同时，第一剂次麻疹 - 风疹联合疫苗（MCV1）覆盖率从2015年的64%提高到2017年的87%，提高了23%。非脊髓灰质炎AFP发病率从2015年的1.2反弹至2017年的4.3。此外，接受三剂及以上口服脊髓灰质炎疫苗（OPV）的AFP病例数从2015年的36%增至2017年的61%，增长了两倍。
在经历2014 - 2015年西非规模最大、破坏性最强的埃博拉病毒病疫情后，利比里亚的免疫服务展现出强劲反弹。免疫接种覆盖率提高，漏种率降低。然而，国家和次国家层面在免疫规划方面仍有改进空间。
