确定能够使免疫规划具有弹性的特征:范围综述。
Identifying characteristics that enable resilient immunisation programmes: a scoping review.
机构信息
Department of Paediatrics, University of Oxford, Oxford, UK.
Merck & Co., Inc, North Wales, Pennsylvania, USA.
出版信息
BMJ Open. 2024 May 28;14(5):e072794. doi: 10.1136/bmjopen-2023-072794.
OBJECTIVES
The COVID-19 pandemic highlighted the fragility of immunisation programmes and resulted in a significant reduction in vaccination rates, with increasing vaccine-preventable disease outbreaks consequently reported. These vulnerabilities underscore the importance of resilient immunisation programmes to ensure optimal performance during crises. To date, a framework for assessing immunisation programme resilience does not exist. We conducted a scoping review of immunisation programmes during times of crisis to identify factors that characterise resilient immunisation programmes, which may inform an Immunisation Programme Resilience Tool.
DESIGN
Scoping review design followed the Arksey and O'Malley framework, and manuscript reporting followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses for Scoping Reviews guidelines.
DATA SOURCES
CINAHL, CENTRAL, Embase, Google Scholar, MEDLINE, PsycINFO and Web of Science and databases were searched between 1 January 2011 and 2 September 2023. Citation searching of identified studies was also performed.
ELIGIBILITY CRITERIA
We included primary empirical peer-reviewed studies that discussed the resilience of immunisation programme to crises, shocks or disruptions.
DATA EXTRACTION AND SYNTHESIS
Two independent reviewers screened records and performed data extraction. We extracted data on study location and design, crisis description, and resilience characteristics discussed, and identified evidence gaps in the literature. Findings were synthesised using tabulation and an evidence gap map.
RESULTS
Thirty-seven studies met the eligibility criteria. These studies captured research conducted across six continents, with most concentrated in Africa, Asia and Europe. One study had a randomised controlled trial design, while 36 studies had observational designs (15 analytical and 21 descriptive). We identified five characteristics of resilient immunisation programmes drawing on the Health System Resilience Index (Integration, Awareness, Resource Availability and Access, Adaptiveness and Self-regulation) and several evidence gaps in the literature.
CONCLUSIONS
To our knowledge, no immunisation programme resilience tool exists. We identified factors from the Health System Resilience Index coupled with factors identified through primary empirical evidence, which may inform development of an immunisation programme resilience tool.
目的
新冠疫情凸显了免疫规划的脆弱性,导致疫苗接种率大幅下降,随后报告了越来越多的疫苗可预防疾病暴发。这些脆弱性突显了具有弹性的免疫规划的重要性,以确保在危机期间的最佳表现。迄今为止,尚无评估免疫规划弹性的框架。我们对危机期间的免疫规划进行了范围综述,以确定构成有弹性的免疫规划的因素,这些因素可能为免疫规划弹性工具提供信息。
设计
采用阿特赛和奥马利的框架进行范围综述设计,手稿报告遵循系统评价和荟萃分析的首选报告项目用于范围综述指南。
数据来源
CINAHL、CENTRAL、Embase、谷歌学术、MEDLINE、PsycINFO 和 Web of Science 以及数据库,检索时间为 2011 年 1 月 1 日至 2023 年 9 月 2 日。还对已确定研究的引文进行了搜索。
入选标准
我们纳入了讨论免疫规划对危机、冲击或干扰的弹性的主要实证同行评议研究。
数据提取和综合
两名独立评审员筛选记录并进行数据提取。我们提取了关于研究地点和设计、危机描述以及讨论的弹性特征的数据,并确定了文献中的证据差距。使用制表和证据差距图对研究结果进行综合。
结果
37 项研究符合入选标准。这些研究涵盖了六大洲的研究,其中大部分集中在非洲、亚洲和欧洲。一项研究采用了随机对照试验设计,而 36 项研究采用了观察性设计(15 项分析性和 21 项描述性)。我们确定了有弹性的免疫规划的五个特征,这些特征借鉴了卫生系统弹性指数(整合、意识、资源可用性和获取、适应性和自我调节),以及文献中的几个证据差距。
结论
据我们所知,目前尚无免疫规划弹性工具。我们从卫生系统弹性指数中确定了一些因素,并结合主要实证证据中确定的因素,这些因素可能为免疫规划弹性工具的开发提供信息。