Department of Social and Preventive Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
Nephrology Unit, Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
PLoS One. 2019 Aug 12;14(8):e0220411. doi: 10.1371/journal.pone.0220411. eCollection 2019.
End-stage renal disease (ESRD) is increasing globally, and renal transplantation (RT) is the preferred renal replacement therapy to treat ESRD. Internationally, there are only a few countries with RT rates above 50 per million population (pmp), while most of the countries have RT rates between 30-40 pmp. The low- and middle-income countries (LMIC) makes up the majority for the RT rates below 20 pmp in which Malaysia belongs to despite its increasing ESRD rates. There is a need to explore the barriers to access RT with targeted solutions to improve the RT rates and service in LMIC. Thus, a qualitative study was undertaken in Malaysia to address this issue.
A qualitative methodological approach was performed between March-May 2018. Semi-structured interviews were used to explore current RT policy and service availability. Key-informants were identified from a detailed stakeholder analysis of RT system in Malaysia. Interviews were digitally audio-recorded, transcribed verbatim, coded with ATLAS.ti software and underwent thematic analysis thoroughly.
Eight key-informants participated in the study. Barriers and related solutions were classified using the socio-ecological model (SEM). As reported, the barriers and solutions of RT in Malaysia are the results of a complex interplay of personal, cultural, and environmental factors. Key barriers are linked to public's attitude and perception towards RT and the unaccommodating practices in the healthcare fraternity for RT. Key-informants provided a systematic solution that shed light on how RT could be improved at each SEM level via effective communication, education and inter-agency collaboration.
The SEM provided a framework to foster a better understanding of current practice, barriers, and solutions to RT in Malaysia. This study is the first to explore the barriers and related solutions to RT comprehensively as a whole. Implications of these findings could prompt a policy change for a better RT service delivery model not just for Malaysia but also for other LMIC. Further stakeholder engagement and evaluation of the systems are required to provide insight into best practices that will help to improve the RT rates and service in Malaysia.
终末期肾病(ESRD)在全球范围内不断增加,肾移植(RT)是治疗 ESRD 的首选肾脏替代疗法。在国际上,只有少数国家的 RT 率超过 50/百万人(pmp),而大多数国家的 RT 率在 30-40 pmp 之间。中低收入国家(LMIC)占 RT 率低于 20 pmp 的大多数国家,马来西亚也属于此类国家,尽管其 ESRD 发病率不断上升。需要探索获得 RT 的障碍,并制定有针对性的解决方案,以提高 LMIC 的 RT 率和服务水平。因此,在马来西亚进行了一项定性研究来解决这个问题。
2018 年 3 月至 5 月期间采用定性方法进行研究。使用半结构式访谈来探索当前的 RT 政策和服务提供情况。从马来西亚 RT 系统的详细利益相关者分析中确定了关键信息提供者。访谈进行了数字音频记录、逐字转录、使用 ATLAS.ti 软件进行编码,并进行了彻底的主题分析。
八名关键信息提供者参与了研究。使用社会生态模型(SEM)对障碍和相关解决方案进行分类。据报道,马来西亚的 RT 障碍和解决方案是个人、文化和环境因素复杂相互作用的结果。主要障碍与公众对 RT 的态度和看法以及医疗保健行业对 RT 的不适应做法有关。关键信息提供者提供了一个系统的解决方案,阐明了如何通过有效的沟通、教育和机构间合作,在每个 SEM 层面上改善 RT。
SEM 提供了一个框架,以更好地理解马来西亚当前的 RT 实践、障碍和解决方案。这项研究首次全面探讨 RT 的障碍和相关解决方案。这些发现的影响可能会促使政策发生变化,以改善马来西亚的 RT 服务提供模式,不仅适用于马来西亚,也适用于其他 LMIC。需要进一步进行利益相关者的参与和对系统的评估,以提供最佳实践的见解,从而帮助提高马来西亚的 RT 率和服务水平。