• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

原发性开角型青光眼的角膜偏离幅度与视野进展。

Corneal deflection amplitude and visual field progression in primary open-angle glaucoma.

机构信息

Department of Ophthalmology, College of Medicine, Yeouido St. Mary's Hospital, The Catholic University of Korea, Seoul, Republic of Korea.

出版信息

PLoS One. 2019 Aug 12;14(8):e0220655. doi: 10.1371/journal.pone.0220655. eCollection 2019.

DOI:10.1371/journal.pone.0220655
PMID:31404083
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6690643/
Abstract

PURPOSE

To investigate the relationship between corneal deflection amplitude and visual field progression rate in patients with primary open-angle glaucoma (POAG).

METHODS

This study included 113 eyes of 65 patients with POAG followed for an average of 4.81 ± 1.24 years. Evaluation of visual field progression rate was performed using mean deviation of standard automated perimetry. Corneal deflection amplitude was measured using Corvis ST (Oculus Optikgeräte GmbH, Wetzlar, Germany). Linear mixed models were performed to determine the relationship between corneal deflection amplitude, intraocular pressure (IOP), and visual field progression rate.

RESULTS

Mean age was 56.36 ± 14.58 years. Baseline average mean deviation was -8.20 ± 9.12 dB and mean treated IOP was 14.38 ± 3.08 mmHg. Average deflection amplitude was 0.90 ± 0.13 mm. In both univariate and multivariate analysis, IOP (P = 0.028 and P < 0.001, respectively) and deflection amplitude (P = 0.034 and P < 0.001, respectively) significantly affected visual field progression rate. Eyes with high IOP and greater deflection amplitude showed faster progression rate.

CONCLUSIONS

Corneal deflection amplitude was significantly related with glaucoma progression. Eyes with greater corneal deflection amplitude showed faster visual field progression rate in patients with POAG.

摘要

目的

研究原发性开角型青光眼（POAG）患者角膜偏离幅度与视野进展率之间的关系。

方法

本研究纳入了 65 例 POAG 患者的 113 只眼，平均随访 4.81±1.24 年。使用标准自动视野计平均偏差评估视野进展率。使用 Corvis ST（德国 Oculus Optikgeräte GmbH）测量角膜偏离幅度。采用线性混合模型确定角膜偏离幅度、眼内压（IOP）和视野进展率之间的关系。

结果

平均年龄为 56.36±14.58 岁。基线平均平均偏差为-8.20±9.12dB，平均治疗 IOP 为 14.38±3.08mmHg。平均偏离幅度为 0.90±0.13mm。在单变量和多变量分析中，IOP（P=0.028 和 P<0.001）和偏离幅度（P=0.034 和 P<0.001）均显著影响视野进展率。IOP 高和偏离幅度大的眼表现出更快的进展速度。

结论

角膜偏离幅度与青光眼进展显著相关。POAG 患者中角膜偏离幅度较大的眼表现出更快的视野进展速度。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cdc/6690643/6a1d75ac1208/pone.0220655.g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cdc/6690643/aa0f8b43f0bc/pone.0220655.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cdc/6690643/460be7629063/pone.0220655.g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cdc/6690643/6a1d75ac1208/pone.0220655.g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cdc/6690643/aa0f8b43f0bc/pone.0220655.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cdc/6690643/460be7629063/pone.0220655.g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cdc/6690643/6a1d75ac1208/pone.0220655.g003.jpg

相似文献

1
Corneal deflection amplitude and visual field progression in primary open-angle glaucoma.原发性开角型青光眼的角膜偏离幅度与视野进展。
PLoS One. 2019 Aug 12;14(8):e0220655. doi: 10.1371/journal.pone.0220655. eCollection 2019.
2
Corneal biomechanical characteristics measured by the CorVis Scheimpflug technology in eyes with primary open-angle glaucoma and normal eyes.应用 Corvis ST 眼前节分析仪测量原发性开角型青光眼和正常眼的角膜生物力学特征。
Acta Ophthalmol. 2016 Aug;94(5):e317-24. doi: 10.1111/aos.12672. Epub 2015 Feb 1.
3
Corneal Biomechanics and Visual Field Progression in Eyes with Seemingly Well-Controlled Intraocular Pressure.眼压似乎得到良好控制的眼中的角膜生物力学和视野进展。
Ophthalmology. 2019 Dec;126(12):1640-1646. doi: 10.1016/j.ophtha.2019.07.023. Epub 2019 Aug 9.
4
Development of a Novel Corneal Concavity Shape Parameter and Its Association with Glaucomatous Visual Field Progression.新型角膜凹陷形状参数的建立及其与青光眼视野进展的关系。
Ophthalmol Glaucoma. 2019 Jan-Feb;2(1):47-54. doi: 10.1016/j.ogla.2018.10.010. Epub 2018 Nov 7.
5
Association between Corneal Deformation Amplitude and Posterior Pole Profiles in Primary Open-Angle Glaucoma.原发性开角型青光眼的角膜变形幅度与后极部形态的相关性研究。
Ophthalmology. 2016 May;123(5):959-64. doi: 10.1016/j.ophtha.2015.12.043. Epub 2016 Feb 11.
6
Corneal Stiffness Parameters Are Predictive of Structural and Functional Progression in Glaucoma Suspect Eyes.角膜硬度参数可预测青光眼疑似眼中的结构和功能进展。
Ophthalmology. 2021 Jul;128(7):993-1004. doi: 10.1016/j.ophtha.2020.11.021. Epub 2020 Nov 25.
7
Diagnostic Efficacy of Normalization of Corneal Deformation Variables by the Intraocular Pressure in Glaucomatous Eyes.眼压对青光眼患者角膜变形变量进行标准化处理的诊断效能
Invest Ophthalmol Vis Sci. 2016 Mar;57(3):1082-6. doi: 10.1167/iovs.15-18569.
8
The Relationship Between Asymmetries of Corneal Properties and Rates of Visual Field Progression in Glaucoma Patients.角膜性质不对称与青光眼患者视野进展速度的关系。
J Glaucoma. 2020 Oct;29(10):872-877. doi: 10.1097/IJG.0000000000001625.
9
[Risk factors for visual field loss progression in patients with primary open-angle glaucoma in Wenzhou area].[温州地区原发性开角型青光眼患者视野缺损进展的危险因素]
Zhonghua Yan Ke Za Zhi. 2019 Oct 11;55(10):777-784. doi: 10.3760/cma.j.issn.0412-4081.2019.10.009.
10
Glaucoma Progression and its Relationship with Corrected and Uncorrected Intraocular Pressure in Eyes with History of Refractive Corneal Surgery.青光眼进展及其与屈光性角膜手术后眼的矫正和未矫正眼内压的关系。
Curr Eye Res. 2018 Sep;43(9):1136-1144. doi: 10.1080/02713683.2018.1467930. Epub 2018 May 1.

引用本文的文献

1
The role of corneal biomechanics in visual field progression of primary open-angle glaucoma with ocular normotension or hypertension: a prospective longitude study.角膜生物力学在眼压正常或升高的原发性开角型青光眼视野进展中的作用：一项前瞻性纵向研究。
Front Bioeng Biotechnol. 2023 May 10;11:1174419. doi: 10.3389/fbioe.2023.1174419. eCollection 2023.
2
Evaluation of corneal biomechanical properties using the ocular response analyzer and the dynamic Scheimpflug-Analyzer Corvis ST in high pressure and normal pressure open-angle glaucoma patients.应用眼部反应分析仪和动态 Scheimpflug 分析系统 Corvis ST 评价高眼压症和正常眼压性青光眼患者的角膜生物力学特性。
PLoS One. 2023 Jan 26;18(1):e0281017. doi: 10.1371/journal.pone.0281017. eCollection 2023.
3

本文引用的文献

1
Changes in Corneal Biomechanics and Intraocular Pressure Following Cataract Surgery.白内障手术后角膜生物力学和眼内压的变化。
Am J Ophthalmol. 2018 Nov;195:26-35. doi: 10.1016/j.ajo.2018.07.025. Epub 2018 Jul 30.
2
[Dynamic Scheimpflug Analyzer (Corvis ST) for measurement of corneal biomechanical parameters : A praxis-related overview].用于测量角膜生物力学参数的动态Scheimpflug分析仪（Corvis ST）：实践相关概述
Ophthalmologe. 2018 Aug;115(8):635-643. doi: 10.1007/s00347-018-0716-y.
3
The effect of air pulse-driven whole eye motion on the association between corneal hysteresis and glaucomatous visual field progression.
Evaluation of Corvis ST tonometer with the updated software in glaucoma practice.在青光眼诊疗中使用更新软件的Corvis ST眼压计的评估。
Int J Ophthalmol. 2022 Mar 18;15(3):438-445. doi: 10.18240/ijo.2022.03.11. eCollection 2022.
4
Association between Iris Biological Features and Corneal Biomechanics in Myopic Eyes.近视眼中虹膜生物学特征与角膜生物力学的相关性研究。
Dis Markers. 2021 Nov 18;2021:5866267. doi: 10.1155/2021/5866267. eCollection 2021.
空气脉冲驱动全眼球运动对角膜滞后与青光眼视野进展之间关系的影响。
Sci Rep. 2018 Feb 14;8(1):2969. doi: 10.1038/s41598-018-21424-8.
4
Characteristics of corneal biomechanical responses detected by a non-contact scheimpflug-based tonometer in eyes with glaucoma.基于非接触式Scheimpflug眼压计检测的青光眼患者眼部角膜生物力学反应特征
Acta Ophthalmol. 2017 Nov;95(7):e556-e563. doi: 10.1111/aos.13466. Epub 2017 Jun 21.
5
The usefulness of CorvisST Tonometry and the Ocular Response Analyzer to assess the progression of glaucoma.CorvisST 眼压测量和眼反应分析仪在评估青光眼进展中的作用。
Sci Rep. 2017 Jan 17;7:40798. doi: 10.1038/srep40798.
6
Detection of Keratoconus With a New Biomechanical Index.利用一种新的生物力学指标检测圆锥角膜
J Refract Surg. 2016 Dec 1;32(12):803-810. doi: 10.3928/1081597X-20160629-01.
7
Comparison of corneal biomechanical properties in normal tension glaucoma patients with different visual field progression speed.不同视野进展速度的正常眼压性青光眼患者角膜生物力学特性的比较
Int J Ophthalmol. 2016 Jul 18;9(7):973-8. doi: 10.18240/ijo.2016.07.06. eCollection 2016.
8
Changes in Corneal Biomechanical Properties after Long-Term Topical Prostaglandin Therapy.长期局部使用前列腺素治疗后角膜生物力学特性的变化
PLoS One. 2016 May 17;11(5):e0155527. doi: 10.1371/journal.pone.0155527. eCollection 2016.
9
The impact of chronic use of prostaglandin analogues on the biomechanical properties of the cornea in patients with primary open-angle glaucoma.原发性开角型青光眼患者长期使用前列腺素类似物对角膜生物力学特性的影响。
Br J Ophthalmol. 2017 Feb;101(2):120-125. doi: 10.1136/bjophthalmol-2016-308432. Epub 2016 May 9.
10
Corneal Hysteresis and Progressive Retinal Nerve Fiber Layer Loss in Glaucoma.青光眼患者的角膜滞后与视网膜神经纤维层的进行性丢失
Am J Ophthalmol. 2016 Jun;166:29-36. doi: 10.1016/j.ajo.2016.02.034. Epub 2016 Mar 3.