Favrod Jérôme, Nguyen Alexandra, Tronche Anne-Marie, Blanc Olivier, Dubreucq Julien, Chereau-Boudet Isabelle, Capdevielle Delphine, Llorca Pierre Michel
La Source, School of Nursing Sciences, HES-SO University of Applied Sciences and Arts of Western Switzerland, Lausanne, Switzerland.
CHU Clermont Ferrand, Service de Psychiatrie B, Université Clermont Auvergne, Clermont-Ferrand, France.
Front Psychiatry. 2019 Jul 26;10:532. doi: 10.3389/fpsyt.2019.00532. eCollection 2019.
The poor efficacy of drug or psychological treatments on the primary negative symptoms of schizophrenia has led to the development of new interventions. The Positive Emotions Program for Schizophrenia (PEPS) is an emotion regulation strategy training that aims to intensify positive emotions and develop positive performance beliefs. A randomized controlled trial showed that PEPS is effective in reducing the composite score of the reduction of experience syndrome (anhedonia and apathy). The present study is designed to evaluate its feasibility in natural conditions to measure external validity of PEPS. Twenty-one participants recruited through the French national network of expert centers followed eight sessions of PEPS and were assessed pre- and posttest with the Scale for Assessment of Negative Symptoms (SANS) and the Personal and Social Performance (PSP). The scales of the SANS were divided into a composite score of the reduction of the ability to experience and a composite score of the reduction of expression. All participants followed the 8 sessions of PEPS, and both composite scores were significantly and clinically improved at posttest. Social functioning assessed with the PSP was also improved. This field test shows that participation in PEPS is accompanied by a reduction of negative symptoms and an improvement of social functioning. Both negative syndromes, reduction of expression and reduction of experience, are improved. Participants are younger than those in previous studies, which may explain this unexpected result. However, this calls for a controlled study with younger participants.
药物或心理治疗对精神分裂症原发性阴性症状疗效不佳,促使了新干预措施的开发。精神分裂症积极情绪项目(PEPS)是一种情绪调节策略训练,旨在增强积极情绪并培养积极的表现信念。一项随机对照试验表明,PEPS在降低体验综合征(快感缺失和冷漠)减轻的综合评分方面有效。本研究旨在评估其在自然条件下的可行性,以衡量PEPS的外部效度。通过法国国家专家中心网络招募的21名参与者接受了8次PEPS课程,并在前后分别用阴性症状评估量表(SANS)和个人与社会表现量表(PSP)进行评估。SANS量表分为体验能力降低的综合评分和表达降低的综合评分。所有参与者都参加了8次PEPS课程,且两个综合评分在测试后均有显著的临床改善。用PSP评估的社会功能也得到了改善。这项现场试验表明,参与PEPS伴随着阴性症状的减轻和社会功能的改善。表达降低和体验降低这两种阴性综合征均得到改善。参与者比之前研究中的参与者更年轻,这可能解释了这一意外结果。然而,这需要对更年轻的参与者进行对照研究。