Mahmoudvand Hossein, Sepahvand Akram, Khatami Mehrdad, Moayyedkazemi Alireza
1Hepatitis Research Center, Lorestan University of Medical Sciences, Khorramabad, Iran.
2Student Research Committee, Lorestan University of Medical Sciences, Khorramabad, Iran.
J Parasit Dis. 2019 Sep;43(3):402-405. doi: 10.1007/s12639-019-01104-8. Epub 2019 Mar 19.
From among intestinal parasites, coccidian intestinal parasites such as (previously known as ), and are well-known as opportunist parasites, particularly in patients with cancer. This study assessed the prevalence of and in patients with cancer in Lorestan Province, Southwest of Iran. This cross-sectional descriptive study was conducted on 87 patients with colorectal cancers, referred to the general hospitals of Lorestan from October 2017 to August 2018. A fresh stool specimen was collected from each subject in a sterile labeled container. The collected stool samples were concentrated through sucrose flotation method and then prepared for Ziehl-Neelsen staining for microscopic examination. Demographic and possible risk factors such as age, sex, education, residence, and unwashed vegetable/fruit consumption were collected by an applied questionnaire. Out of the 87 patients with colorectal cancer, eight (9.2%) were found positive for and infections, with five (5.74%) and three (3.44%) patients positive for and infections, respectively. Results also showed that sex and unwashed vegetable/fruit consumption were significantly associated with the prevalence of these parasites ( < 0.01). The findings revealed the considerable prevalence of and in patients with colorectal cancers. It is therefore essential for gastrointestinal specialists to pay special attention to the prevalence of coccidian parasites in patients with colorectal cancer.
在肠道寄生虫中,球虫类肠道寄生虫如(以前称为)和,作为机会性寄生虫广为人知,尤其是在癌症患者中。本研究评估了伊朗西南部洛雷斯坦省癌症患者中及的感染率。这项横断面描述性研究对2017年10月至2018年8月转诊至洛雷斯坦省综合医院的87例结直肠癌患者进行。从每个受试者收集新鲜粪便标本于无菌带标签容器中。收集的粪便样本通过蔗糖浮选法浓缩,然后制备用于齐-尼氏染色进行显微镜检查。通过应用问卷收集人口统计学和可能的风险因素,如年龄、性别、教育程度、居住地以及未清洗蔬菜/水果的食用情况。在87例结直肠癌患者中,8例(9.2%)被发现和感染呈阳性,分别有5例(5.74%)和3例(3.44%)患者和感染呈阳性。结果还表明,性别和未清洗蔬菜/水果的食用情况与这些寄生虫的感染率显著相关(<0.01)。研究结果揭示了结直肠癌患者中和感染率相当高。因此,胃肠病专家必须特别关注结直肠癌患者中球虫寄生虫的感染率。