Singh A K, Rao K P, Kizer J, Lazarchick J
Department of Pathology and Laboratory Medicine, Medical University of South Carolina, Charleston 29425.
Ann Clin Lab Sci. 1988 Sep-Oct;18(5):384-7.
Although a great deal of information is available in the literature on the frequency, clinical/laboratory findings and significance of lupus anticoagulants in adults, little is known about such acquired inhibitors in children. Clinical and laboratory findings are presented on seven non-hemophiliac children, four females and three males, ranging in ages from three to 14 years, who developed such inhibitors. In most, the inhibitor is a transient phenomena and is not associated with a bleeding or thrombotic diathesis.
虽然文献中有大量关于成人狼疮抗凝物的发生率、临床/实验室检查结果及其意义的信息，但对于儿童获得性此类抑制剂却知之甚少。本文报告了7例非血友病儿童（4例女性，3例男性，年龄3至14岁）发生此类抑制剂的临床和实验室检查结果。多数情况下，该抑制剂是一种短暂现象，与出血或血栓形成素质无关。
