Department of Chemistry , University of Michigan , 930 N. University Avenue , Ann Arbor , Michigan 48109 , United States.
School of Natural Sciences - Chemistry , University of Tasmania , Hobart , Tasmania 7001 , Australia.
J Am Chem Soc. 2019 Aug 21;141(33):13261-13267. doi: 10.1021/jacs.9b06896. Epub 2019 Aug 13.
The treatment of pyridine- and pyrazole-ligated Ni σ-aryl complexes with Selectfluor results in C(sp)-F bond formation under mild conditions. With appropriate design of supporting ligands, diamagnetic Ni σ-aryl fluoride intermediates can be detected spectroscopically and/or isolated during these transformations. These studies demonstrate for the first time that Ni σ-aryl fluoride complexes participate in challenging C(sp)-F bond-forming reductive elimination to yield aryl fluoride products.
用 Selectfluor 处理吡啶和吡唑配位的 Ni σ-芳基配合物，可在温和条件下形成 C(sp)-F 键。通过适当的配体设计，可以在这些转化中通过光谱检测和/或分离出反磁性的 Ni σ-芳基氟化物中间体。这些研究首次证明 Ni σ-芳基氟化物配合物参与了具有挑战性的 C(sp)-F 键形成的还原消除反应，生成芳基氟化物产物。
