Department of Cardiovascular Diseases, Mayo Clinic, Rochester, MN.
Department of Human Movement Sciences, @AgeAmsterdam, Faculty of Behavioural and Movement Sciences, Vrije Universiteit Amsterdam, Amsterdam Movement Sciences, Amsterdam, The Netherlands.
J Am Med Dir Assoc. 2019 Oct;20(10):1351.e13-1351.e25. doi: 10.1016/j.jamda.2019.06.024. Epub 2019 Aug 10.
The aim of this systematic review was to summarize the validity of nutritional screening tools to detect the risk of malnutrition in community-dwelling older adults.
A systematic review and meta-analysis. The protocol for this systematic review was registered in the PROSPERO database (CRD42017072703).
A literature search was performed in PubMed, EMBASE, CINAHL, and Cochrane using the combined terms "malnutrition," "aged," "community-dwelling," and "screening." The time frame of the literature reviewed was from January 1, 2001, to May 18, 2018. Older community-dwellers were defined as follows: individuals with a mean/median age of >65 years who were community-dwellers or attended hospital outpatient clinics and day hospitals. All nutritional screening tools that were validated in community-dwelling older adults against a reference standard to detect the risk of malnutrition, or with malnutrition, were included.
Meta-analyses were performed on the diagnostic accuracy of identified nutritional screening tools validated against the Mini Nutritional Assessment-Long Form (MNA-LF). The symmetric hierarchical summary receiver operating characteristic models were used to estimate test performance.
Of 7713 articles, 35 articles were included in the systematic review, and 9 articles were included in the meta-analysis. Seventeen nutritional screening tools and 10 reference standards were identified. The meta-analyses showed average sensitivities and specificities of 0.95 (95% confidence interval [CI] 0.75-0.99) and 0.95 (95% CI 0.85-0.99) for the Mini Nutritional Assessment-Short Form (MNA-SF; cutoff point ≤11), 0.85 (95% CI 0.80-0.89) and 0.87 (95% CI 0.86-0.89) for the MNA-SF-V1 (MNA-SF using body mass index, cutoff point ≤11), 0.85 (95% CI 0.77-0.89) and 0.84 (95% CI 0.79-0.87) for the MNA-SF-V2 (MNA-SF using calf circumference instead of body mass, cutoff point ≤11), respectively, using MNA-LF as the reference standard.
The MNA-SF, MNA-SF-V1, and MNA-SF-V2 showed good sensitivity and specificity to detect community-dwelling older adults at risk of malnutrition validated against the MNA-LF. Clinicians should consider the use of the cutoff point ≤11 on the MNA-SF, MNA-SF-V1, and MNA-SF-V2 to identify community-dwelling older adults at risk of malnutrition.
本系统评价旨在总结营养筛查工具用于检测社区居住老年人营养不良风险的有效性。
系统评价和荟萃分析。本系统评价的方案已在 PROSPERO 数据库(CRD42017072703)中注册。
在 PubMed、EMBASE、CINAHL 和 Cochrane 中使用“营养不良”“老年人”“社区居住”和“筛查”等联合术语进行文献检索。文献回顾的时间范围为 2001 年 1 月 1 日至 2018 年 5 月 18 日。社区居住的老年人定义如下:平均/中位数年龄>65 岁的个体,他们是社区居住者或在医院门诊和日间医院就诊。纳入了针对社区居住老年人进行验证以检测营养不良风险或营养不良的所有营养筛查工具。
对针对 Mini Nutritional Assessment-Long Form(MNA-LF)进行验证的已确定营养筛查工具的诊断准确性进行荟萃分析。使用对称层次综合受试者工作特征模型来估计测试性能。
在 7713 篇文章中,有 35 篇文章被纳入系统评价,9 篇文章被纳入荟萃分析。确定了 17 种营养筛查工具和 10 种参考标准。荟萃分析显示,Mini Nutritional Assessment-Short Form(MNA-SF;截断值≤11)的平均敏感度和特异度分别为 0.95(95%置信区间[CI] 0.75-0.99)和 0.95(95% CI 0.85-0.99),MNA-SF-V1(使用体重指数的 MNA-SF,截断值≤11)的平均敏感度和特异度分别为 0.85(95% CI 0.80-0.89)和 0.87(95% CI 0.86-0.89),MNA-SF-V2(使用小腿围而不是体重的 MNA-SF,截断值≤11)的平均敏感度和特异度分别为 0.85(95% CI 0.77-0.89)和 0.84(95% CI 0.79-0.87),均以 MNA-LF 为参考标准。
MNA-SF、MNA-SF-V1 和 MNA-SF-V2 对使用 MNA-LF 进行验证的社区居住的有营养不良风险的老年人具有良好的敏感性和特异性。临床医生应考虑使用 MNA-SF、MNA-SF-V1 和 MNA-SF-V2 的截断值≤11 来识别有营养不良风险的社区居住的老年人。