Gastroenterology and Endoscopy Unit, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Università di Milano, Milan, Italy.
Division of Endoscopy, European Institute of Oncology, Milan, Italy.
Dig Liver Dis. 2020 Jan;52(1):38-43. doi: 10.1016/j.dld.2019.07.008. Epub 2019 Aug 10.
Intestinal ultrasound (IUS) examination is a first-line non-invasive imaging procedure for patients with suspicion of bowel diseases.
To assess the feasibility, reproducibility and diagnostic accuracy of a pocket-size ultrasound device (PUD) in identifying the presence of intestinal alterations in patients consecutively recruited to undergo IUS examination.
200 consecutive patients (57% female, 48.8 years) underwent both PUD (two independent investigators) and IUS examination on the same day. Nine ultrasonographic signs were systematically searched for. PUD inter-observer reproducibility was assessed by kappa statistic and ICC. The diagnostic accuracy of PUD as compared to IUS results was assessed by calculating sensitivity, specificity and corresponding positive and negative likelihood ratios.
PUD and IUS examinations were successful in 100% of the patients. PUD reproducibility was good/excellent at evidencing the presence (ICC 0.84) and length (ICC 0.85) of an intestinal tract with thickened wall and abdominal free fluid (ICC 0.87). The diagnostic accuracy of PUD, compared to traditional IUS, was good with regard to the presence of bowel wall thickening (sensitivity 92%, specificity 95%), the length of the thickened bowel (sensitivity 94%, specificity 95%) and the presence of free fluid (sensitivity 81%, specificity 99%).
PUD is a feasible, reproducible and accurate first-line screening tool for the assessment of the gastro-intestinal tract.
肠超声(IUS)检查是疑似肠道疾病患者的一线非侵入性成像程序。
评估口袋大小超声设备(PUD)在识别连续招募进行 IUS 检查的患者肠道改变方面的可行性、可重复性和诊断准确性。
200 名连续患者(57%为女性,48.8 岁)在同一天接受了 PUD(两名独立的研究者)和 IUS 检查。系统搜索了九个超声征象。通过kappa 统计和 ICC 评估 PUD 观察者间的可重复性。通过计算灵敏度、特异性和相应的阳性和阴性似然比,评估 PUD 与 IUS 结果的诊断准确性。
PUD 和 IUS 检查在 100%的患者中均成功进行。PUD 在证明存在(ICC 0.84)和长度(ICC 0.85)增厚的肠壁和腹部游离液方面具有良好/优秀的可重复性。与传统 IUS 相比,PUD 的诊断准确性对于肠壁增厚的存在(灵敏度 92%,特异性 95%)、增厚肠的长度(灵敏度 94%,特异性 95%)和游离液的存在(灵敏度 81%,特异性 99%)均较好。
PUD 是一种可行、可重复和准确的一线筛查工具,用于评估胃肠道。