Zhong Connie S, Richardson Edward T, Laga Canales Alvaro C, Nambudiri Vinod E
Harvard Medical School, Boston, Massachusetts, USA.
Dermatology, Brigham and Women's Hospital, Boston, Massachusetts, USA.
BMJ Case Rep. 2019 Aug 12;12(8):e230142. doi: 10.1136/bcr-2019-230142.
A 69-year-old man with esophageal EBV-positive diffuse large B cell lymphoma status post allogeneic bone marrow transplant (BMT) five months prior presented to his oncologist with three days of maculopapular rash that was initially diagnosed as grade 1 graft-versus-host disease and started on oral prednisone. However, due to worsening of the rash, the patient presented to dermatology clinic, where skin biopsy revealed a diagnosis of erythema multiforme (EM). The patient improved with the use of topical steroids. This case highlights the atypical morphology of post-BMT EM and the potential causes for this atypical appearance.
一名69岁男性，5个月前接受了异基因骨髓移植（BMT），患有食管EBV阳性弥漫性大B细胞淋巴瘤。他因出现斑丘疹3天就诊于肿瘤学家，最初被诊断为1级移植物抗宿主病，并开始口服泼尼松。然而，由于皮疹恶化，患者前往皮肤科诊所，皮肤活检显示诊断为多形红斑（EM）。患者使用外用类固醇后病情好转。该病例突出了BMT后EM的非典型形态以及这种非典型表现的潜在原因。
