Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Department of Ubiquitous Health Informatics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Sci Rep. 2019 Aug 13;9(1):11768. doi: 10.1038/s41598-019-48267-1.
Covert atrial fibrillation (AF) accounts for cryptogenic stroke aetiology in elderly patients and in younger populations. However, asymptomatic AF is difficult to diagnose based on a short electrocardiography (ECG) recording. We evaluated the feasibility of a self-applied continuous ECG monitoring device that can record automatically, easily, and noninvasively in a younger population. We investigated community screening for asymptomatic AF using a wireless single-lead ECG with an electrode embedded in a T-shirt. One hundred men with a CHADS2 score ≥1 who were free from AF and <65 years of age were enrolled. We instructed the participants to wear ECG monitoring devices for at least 4 days/week over 2 months. The proportion of participants with newly detected AF (NDAF) and the monitoring time were evaluated. The mean CHADS2 score was 1.43 ± 0.62. The mean patient age was 52.5 ± 5.4 years. The mean monitoring time was 222 ± 199 hours. NDAF continuing for >30 seconds was detected in 10 participants (10.0%). AF continuing for >6 minutes was detected in 2 participants (2.0%). The T-shirt-type wearable ECG monitoring system was suitable for continuous, daily long-term use among young people with high physical activity, and it had the distinct capability of identifying covert AF.
隐匿性心房颤动(AF)占老年患者和年轻人群中不明原因卒中病因的比例。然而,基于短时间心电图(ECG)记录,隐匿性 AF 很难诊断。我们评估了一种可自动、简便、无创记录的自我应用连续 ECG 监测设备在年轻人群中的应用可行性。我们使用带有嵌入 T 恤电极的无线单导联 ECG 对无症状 AF 进行社区筛查。招募了 100 名 CHADS2 评分≥1 且无 AF 且年龄<65 岁的男性。我们指导参与者佩戴 ECG 监测设备,每周至少 4 天,持续 2 个月。评估了新发现 AF(NDAF)的比例和监测时间。平均 CHADS2 评分为 1.43±0.62。平均患者年龄为 52.5±5.4 岁。平均监测时间为 222±199 小时。在 10 名参与者(10.0%)中检测到持续时间超过 30 秒的 NDAF。在 2 名参与者(2.0%)中检测到持续时间超过 6 分钟的 AF。T 恤式可穿戴 ECG 监测系统适合于具有高身体活动量的年轻人进行连续、日常的长期使用,并且具有明显的识别隐匿性 AF 的能力。