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Longevity in rheumatic fever; based on the experience of 1,042 children observed over a period of 30 years.
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Rheumatic fever and rheumatic heart disease; a twenty year report on 1000 patients followed since childhood.风湿热与风湿性心脏病：对1000例自儿童期起进行随访的患者的20年报告
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Doppler echocardiographic assessment of progression of aortic regurgitation.经多普勒超声心动图评估主动脉瓣反流的进展情况。
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Progression of valvular aortic stenosis in adults: literature review and clinical implications.成人主动脉瓣狭窄的进展：文献综述及临床意义
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Long-term results with the Medtronic-Hall valvular prosthesis.美敦力-霍尔瓣膜假体的长期效果。
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Progression of aortic stenosis. Role of age and concomitant coronary artery disease.主动脉瓣狭窄的进展。年龄及合并冠状动脉疾病的作用。
Chest. 1994 Jun;105(6):1902. doi: 10.1378/chest.105.6.1902a.
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Progression of aortic stenosis in 394 patients: relation to changes in myocardial and mitral valve dysfunction.394例主动脉瓣狭窄患者的病情进展：与心肌和二尖瓣功能障碍变化的关系。
J Am Coll Cardiol. 1995 Feb;25(2):305-10. doi: 10.1016/0735-1097(94)00406-g.
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9
Comparison of Doppler-derived pressure gradient to that determined at cardiac catheterization in adults with aortic valve stenosis: implications for management.成人主动脉瓣狭窄患者中，多普勒衍生压力梯度与心导管检查测定的压力梯度的比较：对管理的意义。
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Hemodynamic progression of adult valvular aortic stenosis.成人瓣膜性主动脉瓣狭窄的血流动力学进展。
Cathet Cardiovasc Diagn. 1986;12(3):145-50.

二尖瓣手术后主动脉瓣疾病的预后。

Prognosis of aortic valve disease following mitral valve surgery.

作者信息

Baria Kinnaresh, Kothari Jignesh, Rathod Divyesh

机构信息

Department of Cardiovascular and Thoracic Surgery, U.N.Mehta Institute of Cardiology and Research Center, Gujarat, India.

出版信息

Kardiochir Torakochirurgia Pol. 2019 Jul;16(2):65-68. doi: 10.5114/kitp.2019.86357. Epub 2019 Jun 28.

DOI:10.5114/kitp.2019.86357
PMID:31410092
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6690147/
Abstract

INTRODUCTION

Little is known about the course of aortic valve disease in patients undergoing mitral valve surgery for rheumatic mitral valve disease. In addition, there are no guidelines regarding the appropriate treatment of mild aortic valve disease while replacing the mitral valve.

AIM

To evaluate the long-term outcome of aortic valve disease and the need for aortic valve surgery in patients with rheumatic mitral valve disease who underwent mitral valve surgery.

MATERIAL AND METHODS

Twenty patients (6 male, 14 female; mean age: 23.4 years, range: 14-41) were followed after mitral valve surgery for a mean period of 14 years. All patients had rheumatic heart disease. Aortic valve function was assessed preoperatively by transthoracic echocardiography and during follow-up.

RESULTS

At the time of mitral valve surgery, 11 (55%) patients had aortic valve disease with aortic regurgitation. Nine (45%) patients had no evidence of aortic valve disease. At second surgery, all patients had aortic valve disease (either pure regurgitation or with stenosis). Most had mild disease at the time of mitral valve surgery. Aortic valve replacement was needed after a mean period of 14.1 years (range: 3-26 years).

CONCLUSIONS

In patients with rheumatic heart disease, a noticeable number of patients have mild aortic valve disease at the time of mitral valve surgery. Only a few progress to severe disease, and aortic valve replacement is rarely needed after a long follow-up period.

摘要

引言

对于风湿性二尖瓣疾病患者在接受二尖瓣手术时主动脉瓣疾病的病程了解甚少。此外，在二尖瓣置换时，对于轻度主动脉瓣疾病的适当治疗尚无指南。

目的

评估接受二尖瓣手术的风湿性二尖瓣疾病患者主动脉瓣疾病的长期预后以及主动脉瓣手术的必要性。

材料与方法

20例患者（6例男性，14例女性；平均年龄：23.4岁，范围：14 - 41岁）在二尖瓣手术后接受了平均14年的随访。所有患者均患有风湿性心脏病。术前通过经胸超声心动图评估主动脉瓣功能，并在随访期间进行评估。

结果

在二尖瓣手术时，11例（55%）患者患有主动脉瓣疾病伴主动脉瓣反流。9例（45%）患者无主动脉瓣疾病证据。在二次手术时，所有患者均患有主动脉瓣疾病（单纯反流或合并狭窄）。大多数患者在二尖瓣手术时病情较轻。平均14.1年（范围：3 - 26年）后需要进行主动脉瓣置换。

结论

在风湿性心脏病患者中，相当数量的患者在二尖瓣手术时患有轻度主动脉瓣疾病。只有少数患者进展为严重疾病，经过长期随访后很少需要进行主动脉瓣置换。