Cancer Communication and Screening Group, Department of Behavioural Science and Health, University College London, London, UK.
e-Health Unit, Department of Primary Care and Population Health, University College London, London, UK.
Psychooncology. 2019 Oct;28(10):1959-1970. doi: 10.1002/pon.5198. Epub 2019 Aug 21.
Many countries are implementing human papillomavirus (HPV)-based cervical screening due to the higher sensitivity of the test compared with cytology. As HPV is sexually transmitted, there may be psychosexual consequences of testing positive for the virus. We aimed to review the literature exploring the psychosexual impact of testing positive for high-risk cervical HPV.
MEDLINE, PsycINFO, CINAHL Plus, Web of Science, and EMBASE were searched with no date limits. We also searched the grey literature, reference lists of included articles and carried out forward citation searching. Eligible studies reported at least one psychosexual outcome among HPV-positive women. Qualitative and quantitative papers were included. We extracted data using a standardised form and carried out a quality assessment for each article. We conducted a narrative synthesis for quantitative studies and a thematic synthesis for qualitative studies.
Twenty-five articles were included. Quantitative study designs were diverse making it difficult to determine the impact that an HPV positive result would have in the context of routine screening. The qualitative literature suggested that psychosexual concerns cover a broad range of aspects relating to women's current and past relationships, both interpersonal and sexual.
The psychosexual impact of testing positive for high-risk cervical HPV is unclear. This review highlights the need for further research in the context of HPV-based cervical screening. As primary HPV testing is introduced more widely, it is important to understand women's responses to testing HPV positive in the cancer screening context to minimise any adverse psychosexual impact.
由于 HPV 检测比细胞学检测更敏感，许多国家正在实施基于 HPV 的宫颈癌筛查。由于 HPV 是通过性传播的，因此 HPV 检测阳性可能会对性心理产生影响。我们旨在综述 HPV 检测阳性对宫颈癌患者性心理影响的相关文献。
对 MEDLINE、PsycINFO、CINAHL Plus、Web of Science 和 EMBASE 进行了无时间限制的检索。我们还检索了灰色文献、纳入文章的参考文献列表，并进行了前瞻性引文搜索。合格的研究报告了 HPV 阳性女性的至少一项性心理结果。纳入定性和定量论文。我们使用标准化表格提取数据，并对每篇文章进行质量评估。我们对定量研究进行了叙述性综合分析，对定性研究进行了主题综合分析。
共纳入 25 篇文章。定量研究设计多种多样，难以确定 HPV 阳性结果在常规筛查背景下的影响。定性文献表明，性心理问题涵盖了与女性当前和过去人际关系相关的广泛方面，包括人际关系和性方面。
HPV 检测阳性对宫颈癌患者性心理的影响尚不清楚。本综述强调了在 HPV 检测基础上进行宫颈癌筛查时进一步研究的必要性。随着 HPV 检测作为一线筛查方法的应用越来越广泛，了解女性在癌症筛查背景下对 HPV 检测阳性的反应，对于减轻任何不良性心理影响非常重要。
