Rebouças Kelly Almeida Andrade Ferreira, Narici Flávio Marinho, Santos Junior Manoel Neres, Neres Nayara Silva de Macêdo, Oliveira Márcio Vasconcelos, Souza Cláudio Lima
Universidade Federal da Bahia (UFBA), Vitória da Conquista, BA, Brazil.
Universidade Federal da Bahia (UFBA), Vitória da Conquista, BA, Brazil; Serviço de Hemoterapia do Sudoeste (SHS), Vitória da Conquista, BA, Brazil.
Hematol Transfus Cell Ther. 2019 Oct-Dec;41(4):324-328. doi: 10.1016/j.htct.2019.03.007. Epub 2019 Jun 17.
The serological screening of blood donors has been instituted by the Brazilian Ministry of Health and is mandatory in the research on several diseases transmissible through blood transfusion. Blood banks need to establish a screening service capable of reducing associated transfusions risks.
The objective of this study was to establish the prevalence of transfusion-transmissible infection markers in donors at a hemotherapy service located in southwest Bahia, Brazil.
A retrospective study was performed between 2010 and 2016. Variables, such as the characterization of donors who were suitable and unsuitable for donation (in clinical screening), stratification by gender and age group and unsuitable samples for reactive test results (in serological screening) by aspecific antibodies against hepatitis B virus (anti-HBc and HBsAg), hepatitis C virus (anti-HCV), human T-lymphotropic virus (anti-HTLV I/II), HIV virus (anti-HIV I/II), chagas disease, and syphilis markers, were evaluated.
Collected data showed that 3.13% of the donors were considered unsuitable for serological screening and that the prevalence of reactive test results was higher in donors aged between 30 and 39 years and in males. The means of the serological markers was 1.09% for syphilis reagents, 0.63% for anti-HIV I/II, 0.51% for anti-HBc and anti-HCV, 0.15% for HBsAg, 0.14% for HTLV I/II and 0.10% for Chagas disease.
These results reflect the importance of awareness campaigns on sexually transmitted diseases and transfusion safety measures taken by hemotherapy services.
巴西卫生部已开展献血者血清学筛查，这在多种经输血传播疾病的研究中是强制性的。血库需要建立一种能够降低相关输血风险的筛查服务。
本研究的目的是确定位于巴西巴伊亚州西南部的一家血液治疗服务机构中献血者输血传播感染标志物的流行情况。
进行了一项2010年至2016年的回顾性研究。评估了各种变量，如适合和不适合献血的献血者特征（临床筛查中）、按性别和年龄组分层以及血清学筛查中因针对乙型肝炎病毒（抗-HBc和HBsAg）、丙型肝炎病毒（抗-HCV）、人类嗜T淋巴细胞病毒（抗-HTLV I/II）、HIV病毒（抗-HIV I/II）、恰加斯病和梅毒标志物的非特异性抗体导致反应性检测结果的不合格样本。
收集的数据显示，3.13%的献血者被认为不适合进行血清学筛查，年龄在30至39岁之间的献血者和男性中反应性检测结果的流行率较高。梅毒试剂的血清学标志物平均值为1.09%，抗-HIV I/II为0.63%，抗-HBc和抗-HCV为0.51%，HBsAg为0.15%，HTLV I/II为0.14%，恰加斯病为0.10%。
这些结果反映了开展性传播疾病宣传活动以及血液治疗服务机构采取输血安全措施的重要性。
