苏丹白尼罗河州男性献血者中的输血传播感染：当前血清流行率和分布的筛查。
Transfusion transmitted infections among male blood donors of White Nile State, Sudan: Screening of the current seroprevalence and distribution.
机构信息
Department of Microbiology, Faculty of Medical Laboratory Sciences, University of El Imam El Mahdi, Kosti, Sudan.
Department of Medical Laboratory Investigations, Kosti Police Hospital, Kosti, Sudan.
出版信息
BMC Res Notes. 2020 Nov 30;13(1):549. doi: 10.1186/s13104-020-05333-6.
OBJECTIVE
Our study planned to investigate the current positivity rate and distribution of the serologic markers of TTIs among male blood donors of the White Nile state, Sudan.
RESULTS
The overall reported seropositive cases of TTIs was 15.91%, and percentages of anti-Human immunodeficiency virus 1/2 (anti-HIV1/2), Hepatitis B virus surface antigen (HBVsAg), anti-Hepatitis C virus (anti-HCV), and anti-Treponema palladium (anti-T. palladium) were 2.61%, 5.57%, 1.40%, and 5.72%, respectively. Out of 10897 donors examined, 0.59% had a serological sign of multiple infections. Furthermore, the odds of testing positive for TTIs were higher in the 28-37 age group (OR: 2.620, 95% CI: 2.324-2.955) and lower in the 38-47 age group (OR: 0.671, 95% CI: 0.567-0.794) compared to individuals of 18-27 years old. Likewise, it is more in individuals of Kosti (OR: 1.122, 95% CI: 0.987-1.277) and Rabak (OR: 1.354, 95% CI: 1.188-1.543) localities compared to Al Douiem locality. Anti-HIV/anti-T. palladium (27.70%) and anti-HIV/HBVsAg (23.07%) were the most frequently detected serologic markers of co-infections, P = 0.002.
目的
本研究旨在调查苏丹白尼罗河州男性献血者中 TTIs 的血清标志物目前的阳性率和分布情况。
结果
报告的 TTIs 血清阳性病例总数为 15.91%，抗人类免疫缺陷病毒 1/2（抗 HIV1/2）、乙型肝炎病毒表面抗原（HBVsAg）、抗丙型肝炎病毒（抗 HCV）和梅毒螺旋体（抗 T. palladium）的百分比分别为 2.61%、5.57%、1.40%和 5.72%。在检查的 10897 名献血者中，有 0.59%的人有多重感染的血清学迹象。此外，28-37 岁年龄组检测出 TTIs 阳性的几率更高（OR：2.620，95%CI：2.324-2.955），而 38-47 岁年龄组（OR：0.671，95%CI：0.567-0.794）则较低与 18-27 岁的个体相比。同样，与 Al Douiem 地区相比，Kosti（OR：1.122，95%CI：0.987-1.277）和 Rabak（OR：1.354，95%CI：1.188-1.543）地区的个体感染率更高。抗 HIV/抗 T. palladium（27.70%）和抗 HIV/抗 HBVsAg（23.07%）是最常见的合并感染血清标志物，P=0.002。
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