PAD4 and von Willebrand Factor Link Inflammation and Thrombosis.
作者信息
Morrell Craig N, Hilt Zachary T, Pariser Daphne N, Maurya Preeti
机构信息
From the Aab Cardiovascular Research Institute (C.N.M., Z.T.H., D.N.P., P.M.), University of Rochester School of Medicine, Box CVRI, NY.
Department of Microbiology and Immunology (C.N.M., D.N.P.), University of Rochester School of Medicine, Box CVRI, NY.
出版信息
Circ Res. 2019 Aug 16;125(5):520-522. doi: 10.1161/CIRCRESAHA.119.315601. Epub 2019 Aug 15.
Abstract
摘要
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JCI Insight. 2019 Mar 7;4(5). doi: 10.1172/jci.insight.122943.
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The Platelet Napoleon Complex-Small Cells, but Big Immune Regulatory Functions.血小板拿破仑情结——小细胞，大免疫调节功能。
Annu Rev Immunol. 2019 Apr 26;37:125-144. doi: 10.1146/annurev-immunol-042718-041607. Epub 2018 Nov 28.
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Role of CD40 and ADAMTS13 in von Willebrand factor-mediated endothelial cell-platelet-monocyte interaction.CD40 和 ADAMTS13 在血管性血友病因子介导的血管内皮细胞-血小板-单核细胞相互作用中的作用。
Proc Natl Acad Sci U S A. 2018 Jun 12;115(24):E5556-E5565. doi: 10.1073/pnas.1801366115. Epub 2018 May 23.
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Spontaneous Secretion of the Citrullination Enzyme PAD2 and Cell Surface Exposure of PAD4 by Neutrophils.中性粒细胞中瓜氨酸化酶PAD2的自发分泌及PAD4在细胞表面的暴露。
Front Immunol. 2017 Sep 25;8:1200. doi: 10.3389/fimmu.2017.01200. eCollection 2017.
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The role of RNA uptake in platelet heterogeneity.RNA摄取在血小板异质性中的作用。
Thromb Haemost. 2017 May 3;117(5):948-961. doi: 10.1160/TH16-11-0873. Epub 2017 Mar 9.
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J Exp Med. 2017 Feb;214(2):439-458. doi: 10.1084/jem.20160530. Epub 2016 Dec 28.
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Prevalence of soluble peptidylarginine deiminase 4 (PAD4) and anti-PAD4 antibodies in autoimmune diseases.自身免疫性疾病中可溶性肽基精氨酸脱亚氨酶4（PAD4）及抗PAD4抗体的患病率。
Clin Rheumatol. 2016 May;35(5):1181-8. doi: 10.1007/s10067-015-3082-z. Epub 2015 Sep 29.
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Peptidylarginine deiminases in citrullination, gene regulation, health and pathogenesis.瓜氨酸化、基因调控、健康与发病机制中的肽基精氨酸脱亚氨酶
Biochim Biophys Acta. 2013 Oct;1829(10):1126-35. doi: 10.1016/j.bbagrm.2013.07.003. Epub 2013 Jul 13.
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Neutrophil histone modification by peptidylarginine deiminase 4 is critical for deep vein thrombosis in mice.组蛋白精氨酸脱亚氨酶 4 对中性粒细胞的修饰作用对小鼠深静脉血栓形成至关重要。
Proc Natl Acad Sci U S A. 2013 May 21;110(21):8674-9. doi: 10.1073/pnas.1301059110. Epub 2013 May 6.
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PAD4 is essential for antibacterial innate immunity mediated by neutrophil extracellular traps.PAD4 对于中性粒细胞胞外诱捕网介导的抗菌先天免疫是必需的。
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