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肝内动脉定位器引导下经颈静脉肝内门体分流术的放置:通过病例系列评估可行性、疗效和技术成功率——一篇符合STROBE标准的文章

Intrahepatic arterial localizer guided transjugular intrahepatic portosystemic shunt placement: Feasibility, efficacy, and technical success assessed by a case series-a STROBE- compliant article.

作者信息

Haochen Wang, Yinghua Zou, Jian Wang

机构信息

Department of Interventional Radiology and Vascular Surgery of Peking university first hospital, Beijing, China.

出版信息

Medicine (Baltimore). 2019 Aug;98(33):e16868. doi: 10.1097/MD.0000000000016868.

Abstract

Transjugular intra-hepatic portosystemic shunts (TIPS) had been considered a standard procedure in patients suffering from portal hypertension. The most challenging step in TIPS placement is blind puncture of the portal vein. We had established a localization method by introducing an Intra-Hepatic Arterial based puncture directing Localizer (IHAL) with the assistance of the enhanced computed tomography (CT) reconstruction. This study aimed to evaluate the feasibility, efficacy, and technical success of this method.From June 2018 to August 2018, 10 consecutive patients suffering from refractory ascites or esophageal gastric bleeding by liver cirrhosis were included in this retrospective study to evaluate feasibility, efficacy, and technical success of enhanced CT assisted IHAL-guided puncture of the portal vein. As a control, 10 patients receiving TIPS placement before Jun 2018 with cone beam CT (CBCT)-guided puncture were included to compare the reduction of portal-systemic pressure gradient (PSPG), portal entry time (PET), the number of puncture, dose area product (DAP) and contrast medium consumption.Technical success was 100% in the study group (IHAL-guided group) and in 90.0% of the control group (CBCT-guided group). Appropriate IHAL point could be achieved in all patients under the enhanced CT reconstruction assistance. The median number of punctures and DAP in IHAL group were significantly less than those in CBCT group. The reduction of PSPG, PET, and contrast medium consumption in IHAL group showed no significant differences than those in CBCT group.Enhanced CT reconstruction assisted IHAL-guided portal vein puncture is technically feasible and a reliable tool for TIPS placement resulting in a significant reduction of the number of punctures and DAP.

摘要

经颈静脉肝内门体分流术(TIPS)曾被认为是门静脉高压患者的标准治疗方法。TIPS置入术中最具挑战性的步骤是门静脉的盲目穿刺。我们借助增强计算机断层扫描(CT)重建技术,引入基于肝内动脉的穿刺导向定位器(IHAL)建立了一种定位方法。本研究旨在评估该方法的可行性、有效性和技术成功率。

2018年6月至2018年8月,本回顾性研究纳入了10例因肝硬化导致难治性腹水或食管胃底出血的连续患者,以评估增强CT辅助IHAL引导下门静脉穿刺的可行性、有效性和技术成功率。作为对照,纳入了10例2018年6月前接受TIPS置入术且采用锥形束CT(CBCT)引导穿刺的患者,以比较门体压力梯度(PSPG)降低情况、门静脉穿刺时间(PET)、穿刺次数、剂量面积乘积(DAP)和造影剂用量。

研究组(IHAL引导组)的技术成功率为100%,对照组(CBCT引导组)为90.0%。在增强CT重建技术的辅助下,所有患者均可获得合适的IHAL穿刺点。IHAL组的穿刺次数中位数和DAP均显著低于CBCT组。IHAL组的PSPG降低值、PET和造影剂用量与CBCT组相比无显著差异。

增强CT重建辅助IHAL引导门静脉穿刺技术上可行,是TIPS置入的可靠工具,可显著减少穿刺次数和DAP。

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