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经皮经脾球囊辅助经颈静脉肝内门体分流术在门静脉闭塞患者中的应用:门静脉再通的可行性、安全性和有效性。

Percutaneous Transsplenic Balloon-Assisted Transjugular Intrahepatic Portosystemic Shunt Placement in Patients with Portal Vein Obliteration for Portal Vein Recanalization: Feasibility, Safety and Effectiveness.

机构信息

Institute for Diagnostic and Interventional Radiology, Hannover Medical School, OE8220 Carl-Neuberg-Straße 1, 30625, Hannover, Germany.

Department of Hepatology, Gastroenterology and Endocrinology, Hannover Medical School, Carl-Neuberg-Straße 1, 30625, Hannover, Germany.

出版信息

Cardiovasc Intervent Radiol. 2022 May;45(5):696-702. doi: 10.1007/s00270-021-03054-2. Epub 2022 Jan 11.

Abstract

PURPOSE

To assess the feasibility, safety and effectiveness of portal vein recanalization (PVR)-transjugular portosystemic shunt (TIPS) placement via splenic access using a balloon puncture technique.

MATERIALS AND METHODS

In a single-center retrospective study from March 2017 to February 2021, 14 consecutive patients with portal hypertension, chronic liver disease and portal vein occlusion or near-complete (> 95%) occlusion were referred for PVR-TIPS placement. Feasibility, safety and effectiveness including procedural characteristics such as technical success, complication profile and splenic access time (SAT), balloon positioning time (BPT), conventional portal vein entry time (CPVET), overall procedure time (OPT), fluoroscopy time (FT), dose-area product (DAP) and air kerma (AK) were evaluated.

RESULTS

Transsplenic PVR-TIPS using balloon puncture technique was technically feasible in 12 of 14 patients (8 men, 49 ± 13 years). In two patients without detectable intrahepatic portal vein branches, TIPS placement was not feasible and both patients were referred for further treatment with nonselective beta blockers and endoscopic variceal ligation. No complications grade > 3 of the Cardiovascular and Interventional Radiological Society of Europe classification system occurred. The SAT was 25 ± 21 min, CPVET was 33 ± 26 min, the OPT was 158 ± 54 min, the FT was 42 ± 22 min, the DAP was 167.84 ± 129.23 Gy*cm and the AK was 1150.70 ± 910.73 mGy.

CONCLUSIONS

Transsplenic PVR-TIPS using a balloon puncture technique is feasible and appears to be safe in our series of patients with obliteration of the portal vein. It expands the interventional options in patients with chronic PVT.

摘要

目的

评估经脾途径球囊穿刺技术行门静脉再通(PVR)-经颈静脉肝内门体分流术(TIPS)的可行性、安全性和有效性。

材料与方法

本研究为单中心回顾性研究,纳入 2017 年 3 月至 2021 年 2 月期间 14 例因门静脉高压、慢性肝病且门静脉闭塞或近乎完全闭塞(>95%)而就诊的患者。评估的内容包括可行性、安全性和有效性,其中有效性包括手术特点,如技术成功率、并发症谱和脾穿刺时间(SAT)、球囊定位时间(BPT)、传统门静脉进入时间(CPVET)、总手术时间(OPT)、透视时间(FT)、剂量面积乘积(DAP)和比释动能(AK)。

结果

在 14 例患者中,12 例(8 例男性,年龄 49±13 岁)经脾途径行球囊穿刺技术 PVR-TIPS 是可行的。在 2 例无法检测到肝内门静脉分支的患者中,TIPS 放置不可行,这 2 例患者均被转诊进一步接受非选择性β受体阻滞剂和内镜下食管静脉曲张结扎治疗。未发生心血管介入放射学会欧洲分类系统 3 级以上的并发症。脾穿刺时间为 25±21 分钟,CPVET 为 33±26 分钟,OPT 为 158±54 分钟,FT 为 42±22 分钟,DAP 为 167.84±129.23Gy*cm,AK 为 1150.70±910.73mGy。

结论

在本系列门静脉闭塞患者中,经脾途径球囊穿刺技术行 PVR-TIPS 是可行且安全的。它为慢性 PVT 患者的介入治疗提供了更多选择。

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