De Aramita, Santra Sougata, Hajra Alakananda, Zyryanov Grigory V, Majee Adinath
Department of Chemistry , Visva-Bharati (A Central University) , Santiniketan 731235 , India.
Department of Organic and Biomolecular Chemistry, Chemical Engineering Institute , Ural Federal University , 19 Mira Street , 620002 Yekaterinburg , Russian Federation.
J Org Chem. 2019 Sep 20;84(18):11735-11740. doi: 10.1021/acs.joc.9b01625. Epub 2019 Sep 3.
A visible-light-promoted regioselective coupling of C(sp)-H of aryl-2-azirine and (diacetoxy)iodobenzene has been reported. Rose Bengal as an organophotoredox catalyst has been used in this reaction. The reaction proceeds under aerobic condition at room temperature. A variety of aryl-2-azirines gives the corresponding acyloxylated azirines under this reaction conditions. The reaction goes through a radical pathway. The protocol is also applicable on gram-scale synthesis.
据报道，可见光促进了芳基-2-氮杂环丙烷的C(sp)-H与（二乙酰氧基）碘苯的区域选择性偶联反应。在该反应中使用了玫瑰红作为有机光氧化还原催化剂。该反应在有氧条件下于室温进行。在这种反应条件下，多种芳基-2-氮杂环丙烷可生成相应的酰氧基化氮杂环丙烷。该反应通过自由基途径进行。该方法也适用于克级规模的合成。
