Ammannati P, Siravo D, Gervasi G B, Gelso E, Baldacci M
Ophthalmological Clinic University of Pisa, Italy.
Ophthalmologica. 1988;197(1):51-5. doi: 10.1159/000309918.
We report a new method of fluorangiography employing a polypeptide fraction from bovine factor VIII that has shown remarkable affinity to the endothelial surface of microvessels. Rabbits injected with this compound, labeled with fluorescein isothiocyanate, show a very delayed disappearance time of fluorescence in retinal vessels when compared with those injected with ordinary fluorescein. This allows a good observation of the late time, which is of great diagnostic advantage for several pathological conditions.
我们报告了一种新的荧光血管造影方法，该方法采用了来自牛因子VIII的一种多肽组分，该组分已显示出对微血管内皮表面具有显著亲和力。注射了用异硫氰酸荧光素标记的这种化合物的兔子，与注射普通荧光素的兔子相比，视网膜血管中的荧光消失时间非常延迟。这使得能够很好地观察晚期情况，这对几种病理状况具有很大的诊断优势。
