Allouch P, Mathonnet D, Legue E, Ghnassia J C
Service de Microbiologie, Centre Hospitalier de Versailles, Chesnay.
Pathol Biol (Paris). 1988 Jun;36(5 Pt 2):690-3.
The gallbladder wall, gallbladder lumen and bile duct intraoperative sampling materials had been examined in 52 patients with an operation on the biliary tract. All patients were treated by only one infusion before operation: 1 g ceftriaxone was given to 26 patients and 2 g ceftriaxone to the 26 others. Bacterial species were isolated on twenty patients. There was no significant difference in infection rate and organism identity between bacterial flora isolated from patients receiving 1 g ceftriaxone and patients receiving 2 g. Isolated germs were enterobacteriaceae (15) streptococci (14) and anaerobic bacteria (8). The mean count of bacteria in bile is 10(4) germs/ml. Half positive sampling materials contains more than one bacterial strain. The bacterial flora isolated from bile has characteristics of mixed flora infection. Ceftriaxone had a good efficacy in antibiotic prophylaxis.
对52例接受胆道手术的患者的胆囊壁、胆囊腔和胆管术中采样材料进行了检查。所有患者术前仅接受一次输液治疗：26例患者给予1克头孢曲松，另外26例患者给予2克头孢曲松。从20例患者中分离出细菌种类。接受1克头孢曲松的患者和接受2克头孢曲松的患者所分离出的细菌菌群在感染率和微生物种类方面没有显著差异。分离出的病菌有肠杆菌科细菌（15例）、链球菌（14例）和厌氧菌（8例）。胆汁中的细菌平均计数为每毫升10⁴个病菌。半数阳性采样材料含有不止一种细菌菌株。从胆汁中分离出的细菌菌群具有混合菌群感染的特征。头孢曲松在抗生素预防方面有良好疗效。
