埃及血吸虫病患者中与胶固素结合免疫复合物相关的寄生虫相关抗原的检测
Detection of parasite related antigens associated with conglutinin binding immune complexes in patients with Schistosoma haematobium.
作者信息
Manca F, Cauda R, Laghi V, Trovatello G, Cantarella S, Tresalti E, Ortona L, Celada F
机构信息
Department of Immunology, XIII USL - University of Genoa, Italy.
出版信息
Trans R Soc Trop Med Hyg. 1988;82(2):254-7. doi: 10.1016/0035-9203(88)90437-3.
An ELISA assay was designed to detect the presence of parasite related antigens associated with circulating immune complexes in patients affected by urinary schistosomiasis. The assay makes use of bovine conglutinin as the immune complex recognition unit and of human anti-Schistosoma antibody as the antigen recognition unit. Using this method we showed that 10 of 15 (67%) patients with a positive polyethylene glycol assay had circulating immune complexes in which parasite antigens could be detected.
设计了一种酶联免疫吸附测定（ELISA）来检测受尿路血吸虫病影响患者中与循环免疫复合物相关的寄生虫相关抗原的存在。该测定利用牛胶固素作为免疫复合物识别单元，利用人抗血吸虫抗体作为抗原识别单元。使用这种方法，我们发现15名聚乙二醇检测呈阳性的患者中有10名（67%）存在可检测到寄生虫抗原的循环免疫复合物。
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