Asia-Pacific Centre for Animal Health, Melbourne Veterinary School, Faculty of Veterinary and Agricultural Science, The University of Melbourne, Victoria, Australia, 3010.
Food Microbiol. 2019 Dec;84:103237. doi: 10.1016/j.fm.2019.06.001. Epub 2019 Jun 5.
Between 1991 and 2014 the per capita notification rate of salmonellosis in Australia increased from 31.9 to 69.7 cases per 100,000 people. Salmonella Typhimurium accounted for nearly half the human cases until the end of 2014. In this study, we used cluster analysis tools to compare S. Typhimurium isolates from a chicken-meat study with those reported to the National Enteric Pathogen Surveillance System (NEPSS) from the coincident human and non-human populations. There was limited phage type diversity within all populations and a lack of specificity of MLVA profiling within phage types. The chicken-meat study isolates were not significantly clustered with the human cases and at least 7 non-human sources, based on typing profiles (PT/MLVA combination), could be implicated as a source of human cases during the same period. In the absence of a strong surveillance system representative of all putative sources, MLVA and phage typing alone or in combination are insufficient to identify the source of human cases.
1991 年至 2014 年间，澳大利亚的沙门氏菌病每 10 万人中的报告发病率从 31.9 例增至 69.7 例。在 2014 年底之前，鼠伤寒沙门氏菌几乎占了人类病例的一半。在这项研究中，我们使用聚类分析工具比较了鸡肉研究中的鼠伤寒沙门氏菌分离株与同期国家肠道病原体监测系统（NEPSS）报告的人类和非人类人群中的分离株。所有人群中的噬菌体类型多样性有限，噬菌体类型内的 MLVA 分析缺乏特异性。基于分型谱（PT/MLVA 组合），鸡肉研究分离株与人类病例和至少 7 个非人类来源没有明显聚类，在同一时期，这些非人类来源可能被认为是人类病例的来源。在缺乏代表所有潜在来源的强大监测系统的情况下，仅使用 MLVA 和噬菌体分型或组合不足以确定人类病例的来源。
