Potential predictors of quality of life in Parkinson's Disease: Sleep and mood disorders.

Sleep Disturbances are a non motor symptom very common in Parkinson's Disease characterized by insomnia, worse quality of sleep and Excessive Daytime Sleepiness. Several factors have been associated with these disorders, especially neuropsychiatric symptoms, such as anxiety and depression. The aim of the study was to investigate the relationship between sleep quality and mood disorders and the effects on Quality of Life in Parkinson's Disease patients. We have enrolled 48 Parkinson's Disease patients divided in two group according to their quality of sleep. All of them completed standardized questionnaires such as Beck Depression Inventory, Hamilton Anxiety Rating Scale, Parkinson Disease Questionnaire, Epworth Sleepiness Scale, Pittsburgh Sleep Quality Index. Inter-group analysis showed a significant difference among two groups in anxiety, depression, excessive daytime sleepiness and quality of sleep. Sleep problems, excessive daytime sleepiness, depressive and anxiety symptoms are frequent in PD patients and are significantly associated each other.