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一名丘脑间脑性卒中患者出现垂直凝视麻痹和间歇性无反应。

Vertical gaze paralysis and intermittent unresponsiveness in a patient with a thalamomesencephalic stroke.

作者信息

Beversdorf D Q, Jenkyn L R, Petrowski J T, Cromwell L D, Nordgren R E

机构信息

Section of Neurology, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire 03756, USA.

出版信息

J Neuroophthalmol. 1995 Dec;15(4):230-5.

PMID:8748560
Abstract

A patient with paralysis of upward gaze and downward gaze, absent oculocephalic reflexes, and absent vertical saccades also demonstrated intermittent stupor over the first 9 days of presentation. Magnetic resonance imaging (MRI) demonstrated an infarct in the tegmentum of the mesencephalon including the right red nucleus and the periaqueductal area, superior to the oculomotor nucleus, and contiguous through the left thalamus. The infarct included the area around the rostral interstitial nucleus of the medial longitudinal fasciculus (riMLF), as well as the midbrain reticular formation. Mechanisms are proposed for the unusual concurrent sign of intermittent unresponsiveness in this case.

摘要

一名向上凝视和向下凝视麻痹、眼前庭反射消失且垂直扫视消失的患者,在就诊的前9天还表现出间歇性昏迷。磁共振成像(MRI)显示中脑被盖部梗死,包括右侧红核和导水管周围区域,位于动眼神经核上方,并通过左侧丘脑相连。梗死区域包括内侧纵束吻侧间质核(riMLF)周围区域以及中脑网状结构。本文提出了该病例中出现间歇性无反应这一异常并发症状的机制。

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Vertical gaze paralysis and intermittent unresponsiveness in a patient with a thalamomesencephalic stroke.一名丘脑间脑性卒中患者出现垂直凝视麻痹和间歇性无反应。
J Neuroophthalmol. 1995 Dec;15(4):230-5.
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[Supranuclear vertical gaze palsy: bilateral thalamo-mesencephalic lesions demonstrated by MRI].[核上性垂直凝视麻痹:MRI显示双侧丘脑-中脑病变]
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Dissociated palsy of vertical saccades: loss of voluntary and visually guided saccades with preservation of reflexive vestibular quick phases.垂直性扫视分离性麻痹:随意性和视觉引导性扫视丧失,而反射性前庭快速相得以保留。
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