Feder J, Gomez J M, Serra-Aguirre F, Musso C G
Department of Physiology, University Institute of Hospital Italiano de Buenos Aires, Argentina.
Indian J Nephrol. 2019 Jul-Aug;29(4):232-234. doi: 10.4103/ijn.IJN_307_17.
Reset osmostat (RO) consists of a change in the normal plasma osmolality threshold (reduction or increase), which consequently induces chronic dysnatremia (hyponatremia or hypernatremia). Although the early papers on RO state that hyponatremic patients with this condition are usually not symptomatic, the current view is that most patients with hyponatremia are symptomatic and should be treated. RO has been associated with a myriad of clinical conditions and has clear diagnostic criteria which are crucial to arrive at the correct diagnosis and treatment.
重置渗透压调节器（RO）是指正常血浆渗透压阈值发生改变（降低或升高），进而引发慢性钠代谢紊乱（低钠血症或高钠血症）。尽管早期关于RO的论文指出，患有这种情况的低钠血症患者通常没有症状，但目前的观点是，大多数低钠血症患者都有症状，应该接受治疗。RO与多种临床病症相关，并有明确的诊断标准，这些标准对于正确的诊断和治疗至关重要。
