Jouve R, Ebagosti A, Blanc M M, Costa G, Serradimigni A, Jouve A
Centre d'évaluation thérapeutique, CHU Timone, faculté de médecine de Marseille.
Arch Mal Coeur Vaiss. 1988 Jun;81 Spec No:159-64.
The prevalence of arterial hypertension, as defined by the W.H.O. (systolic BP greater than 160 mmHg and/or diastolic BP greater than 95 mmHg), and the prevalence of its treatment were studied in 2595 local government employees of Marseilles, aged from 20 to 65 years. The prevalence of hypertension was 17.96 p. 100 (466/2595, including 222 men and 244 women). The prevalence of normal tension was 57.50 p. 100 (1492/2595, including 802 men and 690 women). The prevalence of treated hypertension was 37.98 p. 100 (177/466) divided into 29.27 p. 100 (65/222) in men and 45.90 p. 100 (112/244) in women (p less than 0.0001). Blood pressure was controlled by treatment in 32.30 p. 100 (21/65) of treated men and in 36.61 p. 100 (41/112) of treated women (NS). 81.14 p. 100 (198/244) of hypertensive women and 57/82 p. 100 (399/690) of normotensive women were active (managers, executives). In treated men, the plasma level of apoprotein A1 was decreased and that of apoprotein B was increased. Among men, the global score at Bortner questionnaire was significantly lower in the group of 175 untreated hypertensive patients (176 +/- 46) than in the group of treated hypertensive patients (192 +/- 48, p less than 0.05) and in the group of normotensive subjects (186 +/- 41, p less than 0.05). This indicated that untreated hypertensive men have a tendency to type B pattern and suggested a line of research aimed at a better understanding of the relative failure of anti-hypertensive treatments in the prevention of coronary disease.
根据世界卫生组织的定义（收缩压大于160毫米汞柱和/或舒张压大于95毫米汞柱），对2595名年龄在20至65岁之间的马赛当地政府雇员进行了动脉高血压患病率及其治疗情况的研究。高血压患病率为17.96‰（466/2595，其中男性222人，女性244人）。血压正常者的患病率为57.50‰（1492/2595，其中男性802人，女性690人）。接受治疗的高血压患者患病率为37.98‰（177/466），男性为29.27‰（65/222），女性为45.90‰（112/244）（p<0.0001）。接受治疗的男性中血压得到控制的比例为32.30‰（21/65），女性为36.61‰（41/112）（无显著差异）。81.14‰（198/244）的高血压女性和57.82‰（399/690）的血压正常女性为在职人员（经理、管理人员）。接受治疗的男性中，载脂蛋白A1血浆水平降低，载脂蛋白B血浆水平升高。在男性中，175名未接受治疗的高血压患者组（176±46）的博特纳问卷总体得分显著低于接受治疗的高血压患者组（192±48，p<0.05）和血压正常组（186±41，p<0.05）。这表明未接受治疗的高血压男性有B型性格倾向，并提示了一项旨在更好地理解抗高血压治疗在预防冠心病方面相对失败原因的研究方向。
