Dahan M, Darondeau N, Neukirch F, Jaeger P, Solal A C, Juliard J M, Gourgon R
Service de cardiologie, hôpital Bichat, Paris.
Arch Mal Coeur Vaiss. 1988 Jun;81 Spec No:39-43.
In 45 normotensive subjects (21-84 years) we simultaneously measured: 1) arterial pressure (AP) according to guidelines of the World-health-organization; 2) left ventricular (LV) wall thickness (WT) and antero-posterior radius (r), aortic diameter (AD) by M-mode echo with 2D echo control; 3) isthmus--diaphragm pulse wave delay (PWD) by measurement of time, between the foot of aortic velocity curves, respectively in the isthmus and near the diaphragm; 4) sternal length (L). We derived WT/r ratio, pulse wave velocity (PWV) as the ratio L/PWD, the product AD X PWD and the PWD/AD.
AP, WT/r, PWD, PWV, AD, AD X CFD, PWD/AD are significantly correlated with age (respective r = 0.30, p = 0.05; r = 0.61, p less than 0.001; r = -0.67, p less than 0.001; r = 0.73, p less than 0.001; r = 0.61, p less than 0.001; r = -0.49, p less than 0.001; r = 0.52, p less than 0.001. WT/r is significantly correlated with PWD (r = -0.52, p less than 0.001); PWV (r = 0.50, p less than 0.001); AD (r = 0.44, p less than 0.03); AD X PWD (r = -0.38, p = 0.01) and PWD/AD (r = 0.35, p less than 0.02) but not systolic AP.(ABSTRACT TRUNCATED AT 250 WORDS)
在45名血压正常的受试者（21 - 84岁）中，我们同时测量了：1）根据世界卫生组织指南测量动脉压（AP）；2）通过M型超声心动图并结合二维超声心动图控制测量左心室（LV）壁厚度（WT）和前后半径（r）、主动脉直径（AD）；3）通过测量主动脉峡部和膈肌附近速度曲线波峰之间的时间，得出峡部 - 膈肌脉搏波延迟（PWD）；4）胸骨长度（L）。我们计算了WT/r比值、脉搏波速度（PWV）（等于L/PWD）、AD×PWD以及PWD/AD。
AP、WT/r、PWD、PWV、AD、AD×CFD、PWD/AD与年龄显著相关（各自的r值分别为0.30，p = 0.05；r = 0.61，p＜0.001；r = -0.67，p＜0.001；r = 0.73，p＜0.001；r = 0.61，p＜0.001；r = -0.49，p＜0.001；r = 0.52，p＜0.001）。WT/r与PWD（r = -0.52，p＜0.001）、PWV（r = 0.50，p＜0.001）、AD（r = 0.44，p＜0.03）、AD×PWD（r = -0.38，p = 0.01）和PWD/AD（r = 0.35，p＜0.02）显著相关，但与收缩压AP无关。（摘要截断于250字）
