Jin Shengnan, Sun Song, Yu Jin-Tao, Cheng Jiang
School of Petrochemical Engineering, Jiangsu Key Laboratory of Advanced Catalytic Materials & Technology, Jiangsu Province Key Laboratory of Fine Petrochemical Engineering , Changzhou University , Changzhou 213164 , P. R. China.
J Org Chem. 2019 Sep 6;84(17):11177-11185. doi: 10.1021/acs.joc.9b01088. Epub 2019 Aug 26.
The silver-promoted phosphonation/alkynylation of vinyl in α-aryl α-alkynyl allylic alcohols with phosphine oxide was developed, affording a series of α-alkynyl γ-ketophosphine oxides in moderate to good yields. This procedure involved the radical 3-- cyclization, proceeding with the radical 1,2-alkynyl migration rather than the aryl migration.
实现了银促进的α-芳基α-炔丙基烯丙醇中乙烯基与氧化膦的膦酰化/炔基化反应，以中等至良好的产率得到了一系列α-炔丙基γ-酮基氧化膦。该过程涉及自由基3-环化，通过自由基1,2-炔基迁移而非芳基迁移进行。
