Henderson N, Stanescu V, Cauchoix J
Institut de Recherche sur les Maladies du Squelette, Berck-sur-Mer.
C R Acad Sci III. 1988;307(7):403-6.
Nucleolysis using chondroitinase ABC was studied using the rabbit's intervertebral lumbar disc. The purpose was to find a possible alternative to chymopapain which is commonly used in the management of sciatica due to disc herniation. The injection of 1 U of the enzyme into the nucleus pulposus gave significant histological and biochemical changes in all twelve discs studied.
使用兔腰椎间盘研究了用软骨素酶ABC进行髓核溶解。目的是找到一种可能替代常用于治疗椎间盘突出症所致坐骨神经痛的木瓜凝乳蛋白酶的方法。向髓核内注射1单位该酶，在所研究的所有12个椎间盘中均产生了显著的组织学和生化变化。
